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. Author manuscript; available in PMC: 2017 May 1.
Published in final edited form as: Bone. 2016 Feb 24;86:30–35. doi: 10.1016/j.bone.2016.02.011

Table 2.

Discrimination of major osteoporotic fracture (MOF), hip fracture and femoral neck osteoporosis (DXA FN BMD T-score ≤ −2.5). Area under the curve (AUC) determined from receiver operating characteristic (ROC) analysis. Mean and 95 % confidence interval.

AUC MOFa 10 years AUC hip fracture 10 years AUC femoral neck osteoporosis
Age alone 0.59 (0.57, 0.61) 0.68 (0.65, 0.71) 0.64 (0.61, 0.65)
Age + DXR-BMD 0.65 (0.63, 0.67) 0.69 (0.66, 0.72) 0.76 (0.74, 0.77)
Age + DXA FN BMD 0.68 (0.66, 0.70) 0.75 (0.72, 0.77) -
Age + FRAX (no BMD) 0.64 (0.61, 0.65) 0.70 (0.67, 0.73) 0.69 (0.67, 0.71)
Age + DXA L2-L4 BMD 0.65 (0.63, 0.67) 0.69 (0.65, 0.71) -
Age + DXR-BMD + FRAX 0.67 (0.65, 0.69) 0.71 (0.68, 0.74) -
Age + DXR-BMD + prior fracture 0.67 (0.65, 0.69) 0.71 (0.67, 0.73) -
Age + DXA FN BMD + FRAX 0.69 (0.67, 0.70) 0.76 (0.73, 0.78) -
a

Clinical spine, hip, forearm or shoulder fracture.

BMD: bone mineral density; DXA FN: femoral neck BMD by DXA; DXR: metacarpal BMD estimated by digital X-ray radiogrammetry