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. Author manuscript; available in PMC: 2017 May 1.
Published in final edited form as: Bone. 2016 Feb 24;86:30–35. doi: 10.1016/j.bone.2016.02.011

Table 3.

Ten year incidence of fracture by DXA FN BMD, FRAX (no BMD) and DXR-BMD and sensitivity to DXA FN T-score ≤ −2.5 of FRAX (no BMD) and DXR-BMD.

Cumulative percentage of population Threshold Major osteoporotic fracture 10 year (%) Hip fracture 10 year (%) Sensitivity to DXA FN T-score ≤ −2.5 (%)
DXA FN (g/cm2) FRAX hip (%) FRAX MOF (%) DXR (g/cm2) DXA FN FRAX DXR DXA FN FRAX DXR FRAX hip FRAX MOF DXR
65–69 years, N = 2343
0% - - - - - - - - - - - - -
10% 0.539 6.8 24.6 0.433 24.8 21.6 24.2 5.9 6.8 5.1 26 18 25
20% 0.582 4.5 19.3 0.456 21.8 19.7 21.6 4.9 5.6 3.4 39 38 43
30% 0.611 3.5 17.5 0.472 22.1 19.1 21.1 6.1 4.0 3.7 53 49 58
40% 0.639 2.9 15.4 0.488 20.0 18.1 19.6 5.2 4.1 3.5 62 57 70
50% 0.663 2.4 12.1 0.500 18.7 17.4 18.0 4.8 4.1 3.2 73 65 79
60% 0.689 2.0 10.8 0.515 17.1 16.2 16.1 4.1 4.0 3.1 83 80 85
70% 0.715 1.7 10.1 0.532 15.4 15.0 15.2 3.7 3.5 3.2 89 89 91
80% 0.753 1.4 9.4 0.551 14.7 14.1 14.4 3.4 3.4 3.2 94 94 97
90% 0.818 1.1 8.7 0.578 13.6 13.7 13.6 3.2 3.2 2.9 99 98 99
100% 1.270 0.4 5.0 0.678 12.9 12.9 12.9 2.9 2.9 2.9 100 100 100
70–74 years, N = 1674
0% - - - - - - - - - - - - -
10% 0.515 12.8 31.0 0.414 34.0 25.3 29.6 15.2 12.7 12.6 18 19 24
20% 0.551 9.0 24.3 0.437 29.2 24.4 27.8 12.7 12.0 10.5 34 31 40
30% 0.576 7.0 21.9 0.453 26.2 23.3 25.0 10.8 9.2 9.2 44 43 55
40% 0.606 5.9 19.6 0.467 25.4 21.6 22.5 10.5 9.2 8.2 56 55 69
50% 0.633 4.8 16.6 0.482 23.1 20.6 21.4 9.2 8.7 8.0 68 62 81
60% 0.657 4.0 14.1 0.496 21.7 20.3 20.1 8.3 7.7 7.4 77 73 87
70% 0.682 3.3 12.8 0.511 20.7 19.0 19.8 7.8 7.4 7.0 84 84 93
80% 0.718 2.8 11.9 0.529 19.7 18.2 19.0 7.3 7.1 6.8 92 93 96
90% 0.777 2.3 10.9 0.557 18.8 17.7 18.2 6.8 6.5 6.5 97 97 98
100% 1.084 0.8 6.3 0.669 17.2 17.2 17.2 6.2 6.2 6.2 100 100 100
75–79 years, N = 847
0% - - - - - - - - - - - - -
10% 0.500 21.9 38.2 0.395 40.2 31.7 37.2 21.4 16.7 15.5 15 15 19
20% 0.533 15.2 30.6 0.414 37.1 29.2 31.0 19.0 14.2 13.0 28 29 35
30% 0.558 11.7 27.9 0.433 34.2 30.5 29.5 18.2 14.2 13.0 43 44 49
40% 0.586 9.7 25.5 0.447 32.1 27.8 27.3 15.9 14.5 11.8 57 57 62
50% 0.606 8.2 22.2 0.458 31.7 28.3 25.9 16.5 13.7 11.6 67 64 69
60% 0.631 7.3 19.1 0.471 29.9 27.9 26.6 14.5 12.6 10.5 74 77 78
70% 0.659 6.2 17.2 0.484 28.2 26.5 27.0 13.5 12.2 10.5 84 84 86
80% 0.693 5.2 15.6 0.504 27.0 25.0 25.4 12.2 11.9 10.2 91 91 93
90% 0.743 4.2 14.0 0.539 25.1 24.0 24.7 10.9 10.8 10.4 95 95 98
100% 1.298 0.8 5.4 0.637 23.5 23.5 23.5 10.3 10.3 10.3 100 100 100
80+ years, N = 414
0% - - - - - - - - - - - - -
10% 0.472 27.6 45.7 0.377 61.5 31.6 39.5 41.5 22.0 24.4 12 13 16
20% 0.499 21.0 37.1 0.395 43.6 28.6 33.3 24.4 18.3 17.1 26 23 30
30% 0.529 16.7 33.9 0.409 41.4 28.0 36.1 25.2 17.1 18.5 37 38 43
40% 0.551 14.2 31.9 0.420 39.9 32.1 35.2 25.3 17.7 17.6 48 52 56
50% 0.577 12.2 29.3 0.432 38.6 34.2 36.0 23.8 19.4 18.4 59 61 67
60% 0.608 11.0 25.1 0.449 35.3 34.5 34.3 21.4 19.8 18.5 71 69 76
70% 0.633 9.7 22.3 0.461 33.5 35.7 33.1 19.4 19.0 18.0 85 81 84
80% 0.670 8.5 21.0 0.482 31.3 32.9 30.3 18.4 18.4 16.1 93 93 90
90% 0.721 7.4 19.4 0.507 29.6 30.3 29.7 16.7 16.7 15.9 98 98 95
100% 1.074 4.5 14.5 0.677 28.5 28.5 28.5 15.5 15.5 15.5 100 100 100

BMD: bone mineral density; DXA FN: femoral neck BMD by DXA; DXR: BMD by digital X-ray radiogrammetry; MOF: major osteoporotic fracture (clinical spine, hip, forearm or shoulder fracture)