Table 3.
Cumulative percentage of population | Threshold | Major osteoporotic fracture 10 year (%) | Hip fracture 10 year (%) | Sensitivity to DXA FN T-score ≤ −2.5 (%) | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DXA FN (g/cm2) | FRAX hip (%) | FRAX MOF (%) | DXR (g/cm2) | DXA FN | FRAX | DXR | DXA FN | FRAX | DXR | FRAX hip | FRAX MOF | DXR | |
65–69 years, N = 2343 | |||||||||||||
0% | - | - | - | - | - | - | - | - | - | - | - | - | - |
10% | 0.539 | 6.8 | 24.6 | 0.433 | 24.8 | 21.6 | 24.2 | 5.9 | 6.8 | 5.1 | 26 | 18 | 25 |
20% | 0.582 | 4.5 | 19.3 | 0.456 | 21.8 | 19.7 | 21.6 | 4.9 | 5.6 | 3.4 | 39 | 38 | 43 |
30% | 0.611 | 3.5 | 17.5 | 0.472 | 22.1 | 19.1 | 21.1 | 6.1 | 4.0 | 3.7 | 53 | 49 | 58 |
40% | 0.639 | 2.9 | 15.4 | 0.488 | 20.0 | 18.1 | 19.6 | 5.2 | 4.1 | 3.5 | 62 | 57 | 70 |
50% | 0.663 | 2.4 | 12.1 | 0.500 | 18.7 | 17.4 | 18.0 | 4.8 | 4.1 | 3.2 | 73 | 65 | 79 |
60% | 0.689 | 2.0 | 10.8 | 0.515 | 17.1 | 16.2 | 16.1 | 4.1 | 4.0 | 3.1 | 83 | 80 | 85 |
70% | 0.715 | 1.7 | 10.1 | 0.532 | 15.4 | 15.0 | 15.2 | 3.7 | 3.5 | 3.2 | 89 | 89 | 91 |
80% | 0.753 | 1.4 | 9.4 | 0.551 | 14.7 | 14.1 | 14.4 | 3.4 | 3.4 | 3.2 | 94 | 94 | 97 |
90% | 0.818 | 1.1 | 8.7 | 0.578 | 13.6 | 13.7 | 13.6 | 3.2 | 3.2 | 2.9 | 99 | 98 | 99 |
100% | 1.270 | 0.4 | 5.0 | 0.678 | 12.9 | 12.9 | 12.9 | 2.9 | 2.9 | 2.9 | 100 | 100 | 100 |
70–74 years, N = 1674 | |||||||||||||
0% | - | - | - | - | - | - | - | - | - | - | - | - | - |
10% | 0.515 | 12.8 | 31.0 | 0.414 | 34.0 | 25.3 | 29.6 | 15.2 | 12.7 | 12.6 | 18 | 19 | 24 |
20% | 0.551 | 9.0 | 24.3 | 0.437 | 29.2 | 24.4 | 27.8 | 12.7 | 12.0 | 10.5 | 34 | 31 | 40 |
30% | 0.576 | 7.0 | 21.9 | 0.453 | 26.2 | 23.3 | 25.0 | 10.8 | 9.2 | 9.2 | 44 | 43 | 55 |
40% | 0.606 | 5.9 | 19.6 | 0.467 | 25.4 | 21.6 | 22.5 | 10.5 | 9.2 | 8.2 | 56 | 55 | 69 |
50% | 0.633 | 4.8 | 16.6 | 0.482 | 23.1 | 20.6 | 21.4 | 9.2 | 8.7 | 8.0 | 68 | 62 | 81 |
60% | 0.657 | 4.0 | 14.1 | 0.496 | 21.7 | 20.3 | 20.1 | 8.3 | 7.7 | 7.4 | 77 | 73 | 87 |
70% | 0.682 | 3.3 | 12.8 | 0.511 | 20.7 | 19.0 | 19.8 | 7.8 | 7.4 | 7.0 | 84 | 84 | 93 |
80% | 0.718 | 2.8 | 11.9 | 0.529 | 19.7 | 18.2 | 19.0 | 7.3 | 7.1 | 6.8 | 92 | 93 | 96 |
90% | 0.777 | 2.3 | 10.9 | 0.557 | 18.8 | 17.7 | 18.2 | 6.8 | 6.5 | 6.5 | 97 | 97 | 98 |
100% | 1.084 | 0.8 | 6.3 | 0.669 | 17.2 | 17.2 | 17.2 | 6.2 | 6.2 | 6.2 | 100 | 100 | 100 |
75–79 years, N = 847 | |||||||||||||
0% | - | - | - | - | - | - | - | - | - | - | - | - | - |
10% | 0.500 | 21.9 | 38.2 | 0.395 | 40.2 | 31.7 | 37.2 | 21.4 | 16.7 | 15.5 | 15 | 15 | 19 |
20% | 0.533 | 15.2 | 30.6 | 0.414 | 37.1 | 29.2 | 31.0 | 19.0 | 14.2 | 13.0 | 28 | 29 | 35 |
30% | 0.558 | 11.7 | 27.9 | 0.433 | 34.2 | 30.5 | 29.5 | 18.2 | 14.2 | 13.0 | 43 | 44 | 49 |
40% | 0.586 | 9.7 | 25.5 | 0.447 | 32.1 | 27.8 | 27.3 | 15.9 | 14.5 | 11.8 | 57 | 57 | 62 |
50% | 0.606 | 8.2 | 22.2 | 0.458 | 31.7 | 28.3 | 25.9 | 16.5 | 13.7 | 11.6 | 67 | 64 | 69 |
60% | 0.631 | 7.3 | 19.1 | 0.471 | 29.9 | 27.9 | 26.6 | 14.5 | 12.6 | 10.5 | 74 | 77 | 78 |
70% | 0.659 | 6.2 | 17.2 | 0.484 | 28.2 | 26.5 | 27.0 | 13.5 | 12.2 | 10.5 | 84 | 84 | 86 |
80% | 0.693 | 5.2 | 15.6 | 0.504 | 27.0 | 25.0 | 25.4 | 12.2 | 11.9 | 10.2 | 91 | 91 | 93 |
90% | 0.743 | 4.2 | 14.0 | 0.539 | 25.1 | 24.0 | 24.7 | 10.9 | 10.8 | 10.4 | 95 | 95 | 98 |
100% | 1.298 | 0.8 | 5.4 | 0.637 | 23.5 | 23.5 | 23.5 | 10.3 | 10.3 | 10.3 | 100 | 100 | 100 |
80+ years, N = 414 | |||||||||||||
0% | - | - | - | - | - | - | - | - | - | - | - | - | - |
10% | 0.472 | 27.6 | 45.7 | 0.377 | 61.5 | 31.6 | 39.5 | 41.5 | 22.0 | 24.4 | 12 | 13 | 16 |
20% | 0.499 | 21.0 | 37.1 | 0.395 | 43.6 | 28.6 | 33.3 | 24.4 | 18.3 | 17.1 | 26 | 23 | 30 |
30% | 0.529 | 16.7 | 33.9 | 0.409 | 41.4 | 28.0 | 36.1 | 25.2 | 17.1 | 18.5 | 37 | 38 | 43 |
40% | 0.551 | 14.2 | 31.9 | 0.420 | 39.9 | 32.1 | 35.2 | 25.3 | 17.7 | 17.6 | 48 | 52 | 56 |
50% | 0.577 | 12.2 | 29.3 | 0.432 | 38.6 | 34.2 | 36.0 | 23.8 | 19.4 | 18.4 | 59 | 61 | 67 |
60% | 0.608 | 11.0 | 25.1 | 0.449 | 35.3 | 34.5 | 34.3 | 21.4 | 19.8 | 18.5 | 71 | 69 | 76 |
70% | 0.633 | 9.7 | 22.3 | 0.461 | 33.5 | 35.7 | 33.1 | 19.4 | 19.0 | 18.0 | 85 | 81 | 84 |
80% | 0.670 | 8.5 | 21.0 | 0.482 | 31.3 | 32.9 | 30.3 | 18.4 | 18.4 | 16.1 | 93 | 93 | 90 |
90% | 0.721 | 7.4 | 19.4 | 0.507 | 29.6 | 30.3 | 29.7 | 16.7 | 16.7 | 15.9 | 98 | 98 | 95 |
100% | 1.074 | 4.5 | 14.5 | 0.677 | 28.5 | 28.5 | 28.5 | 15.5 | 15.5 | 15.5 | 100 | 100 | 100 |
BMD: bone mineral density; DXA FN: femoral neck BMD by DXA; DXR: BMD by digital X-ray radiogrammetry; MOF: major osteoporotic fracture (clinical spine, hip, forearm or shoulder fracture)