Table 1.
Characteristics of women in analytic population
| Characteristicsa | CIN3 (N = 17) | Cervical cancer (N = 21) |
|---|---|---|
| Age (years), mean (SD) | 29.4 (9.1) | 45.0 (11.1) |
| Age (years), n (%) | ||
| <25 | 7 (41.2) | — |
| 25–34 | 6 (35.3) | 5 (23.8) |
| 35–44 | 2 (11.8) | 7 (33.3) |
| 45–54 | 2 (11.8) | 3 (14.3) |
| ≥55 | — | 6 (28.6) |
| Education, n (%) | ||
| High/vocational school or less | 6 (37.5) | 12 (70.6) |
| Some college or more | 10 (62.5) | 5 (29.4) |
| Number of sexual partners, n (%) | ||
| ≤5 | 7 (43.8) | 8 (50.0) |
| >5 | 9 (56.2) | 8 (50.0) |
| Age at first sexual contact (years), mean (SD) | 16.2 (3.7) | 16.5 (2.3) |
| Age at first sexual contact (years), n (%) | ||
| <15 | 3 (17.6) | 4 (23.5) |
| 15–18 | 9 (52.9) | 7 (41.2) |
| ≥18 | 5 (29.4) | 6 (35.3) |
| Smoking, n (%) | ||
| Never or former | 6 (35.3) | 11 (64.7) |
| Current | 11 (64.7) | 6 (35.3) |
| HPV DNA integration statusb, n (%) | ||
| Episomal | 9 (53.9) | 6 (28.6) |
| Integrated | 8 (47.1) | 15 (71.4) |
Numbers may not add to total due to missing values. SD, Standard deviation.
aAt the baseline questionnaire.
bHPV DNA integration assays was performed in 16 women with CIN3 diagnosis (17 samples) and 20 women with cancer diagnosis (21 samples). One woman with CIN3 had two samples (one integrated and one not integrated) and one women with cancer also had two samples (non-integrated). DNA from 2 samples in two different women diagnosed with CIN3 and 6 samples in six different women diagnosed with cancer did not amplified correctly and the integration assays could not be not run.