Extended Data Table 1. Number and genotype of progeny resulting from crosses of 11B3ff/+;Ella-cre female mice with Ella-cre male mice.
Progeny genotype |
11B3+/Δ | 11B3+/+ |
---|---|---|
Predicted | 47 | 47 |
Observed | 0* | 69 |
No 11B3-deleted pup was produced from 11B3fl/+ female breeders with germline Ella-cre, while 25 out of 94 pups were genotyped as 11B3fl/+ without recombination.
P = 2.8 × 10−7 (Chi-squared test).