Skip to main content
PMC home page
British Heart Journal logoLink to British Heart Journal
. 1995 Apr;73(4):304–305. doi: 10.1136/hrt.73.4.304

Role of acadesine in clinical myocardial protection.

A M Alkhulaifi 1, W B Pugsley 1
PMCID: PMC483821  PMID: 7756061

Full text

PDF
304

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Ambrosio G., Jacobus W. E., Mitchell M. C., Litt M. R., Becker L. C. Effects of ATP precursors on ATP and free ADP content and functional recovery of postischemic hearts. Am J Physiol. 1989 Feb;256(2 Pt 2):H560–H566. doi: 10.1152/ajpheart.1989.256.2.H560. [DOI] [PubMed] [Google Scholar]
  2. Belardinelli L., Linden J., Berne R. M. The cardiac effects of adenosine. Prog Cardiovasc Dis. 1989 Jul-Aug;32(1):73–97. doi: 10.1016/0033-0620(89)90015-7. [DOI] [PubMed] [Google Scholar]
  3. Cronstein B. N., Kramer S. B., Weissmann G., Hirschhorn R. Adenosine: a physiological modulator of superoxide anion generation by human neutrophils. J Exp Med. 1983 Oct 1;158(4):1160–1177. doi: 10.1084/jem.158.4.1160. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Cronstein B. N., Levin R. I., Belanoff J., Weissmann G., Hirschhorn R. Adenosine: an endogenous inhibitor of neutrophil-mediated injury to endothelial cells. J Clin Invest. 1986 Sep;78(3):760–770. doi: 10.1172/JCI112638. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Ely S. W., Mentzer R. M., Jr, Lasley R. D., Lee B. K., Berne R. M. Functional and metabolic evidence of enhanced myocardial tolerance to ischemia and reperfusion with adenosine. J Thorac Cardiovasc Surg. 1985 Oct;90(4):549–556. [PubMed] [Google Scholar]
  6. Foley J. M., Adams G. R., Meyer R. A. Utility of AICAr for metabolic studies is diminished by systemic effects in situ. Am J Physiol. 1989 Sep;257(3 Pt 1):C488–C494. doi: 10.1152/ajpcell.1989.257.3.C488. [DOI] [PubMed] [Google Scholar]
  7. Galiñanes M., Bullough D., Mullane K. M., Hearse D. J. Sustained protection by acadesine against ischemia- and reperfusion-induced injury. Studies in the transplanted rat heart. Circulation. 1992 Aug;86(2):589–597. doi: 10.1161/01.cir.86.2.589. [DOI] [PubMed] [Google Scholar]
  8. Glower D. D., Spratt J. A., Newton J. R., Wolfe J. A., Rankin J. S., Swain J. L. Dissociation between early recovery of regional function and purine nucleotide content in postischaemic myocardium in the conscious dog. Cardiovasc Res. 1987 May;21(5):328–336. doi: 10.1093/cvr/21.5.328. [DOI] [PubMed] [Google Scholar]
  9. Gruber H. E., Hoffer M. E., McAllister D. R., Laikind P. K., Lane T. A., Schmid-Schoenbein G. W., Engler R. L. Increased adenosine concentration in blood from ischemic myocardium by AICA riboside. Effects on flow, granulocytes, and injury. Circulation. 1989 Nov;80(5):1400–1411. doi: 10.1161/01.cir.80.5.1400. [DOI] [PubMed] [Google Scholar]
  10. Jennings R. B., Hawkins H. K., Lowe J. E., Hill M. L., Klotman S., Reimer K. A. Relation between high energy phosphate and lethal injury in myocardial ischemia in the dog. Am J Pathol. 1978 Jul;92(1):187–214. [PMC free article] [PubMed] [Google Scholar]
  11. Leung J. M., Stanley T., 3rd, Mathew J., Curling P., Barash P., Salmenpera M., Reves J. G., Hollenberg M., Mangano D. T. An initial multicenter, randomized controlled trial on the safety and efficacy of acadesine in patients undergoing coronary artery bypass graft surgery. SPI Research Group. Anesth Analg. 1994 Mar;78(3):420–434. doi: 10.1213/00000539-199403000-00002. [DOI] [PubMed] [Google Scholar]
  12. Li Y., Kloner R. A. The cardioprotective effects of ischemic 'preconditioning' are not mediated by adenosine receptors in rat hearts. Circulation. 1993 May;87(5):1642–1648. doi: 10.1161/01.cir.87.5.1642. [DOI] [PubMed] [Google Scholar]
  13. Marcus M. L., Chilian W. M., Kanatsuka H., Dellsperger K. C., Eastham C. L., Lamping K. G. Understanding the coronary circulation through studies at the microvascular level. Circulation. 1990 Jul;82(1):1–7. doi: 10.1161/01.cir.82.1.1. [DOI] [PubMed] [Google Scholar]
  14. Mentzer R. M., Jr, Ely S. W., Lasley R. D., Berne R. M. The acute effects of AICAR on purine nucleotide metabolism and postischemic cardiac function. J Thorac Cardiovasc Surg. 1988 Feb;95(2):286–293. [PubMed] [Google Scholar]
  15. Mitsos S. E., Jolly S. R., Lucchesi B. R. Protective effects of AICAriboside in the globally ischemic isolated cat heart. Pharmacology. 1985;31(3):121–131. doi: 10.1159/000138107. [DOI] [PubMed] [Google Scholar]
  16. Olafsson B., Forman M. B., Puett D. W., Pou A., Cates C. U., Friesinger G. C., Virmani R. Reduction of reperfusion injury in the canine preparation by intracoronary adenosine: importance of the endothelium and the no-reflow phenomenon. Circulation. 1987 Nov;76(5):1135–1145. doi: 10.1161/01.cir.76.5.1135. [DOI] [PubMed] [Google Scholar]
  17. Reimer K. A., Jennings R. B., Hill M. L. Total ischemia in dog hearts, in vitro 2. High energy phosphate depletion and associated defects in energy metabolism, cell volume regulation, and sarcolemmal integrity. Circ Res. 1981 Oct;49(4):901–911. doi: 10.1161/01.res.49.4.901. [DOI] [PubMed] [Google Scholar]
  18. Sabina R. L., Kernstine K. H., Boyd R. L., Holmes E. W., Swain J. L. Metabolism of 5-amino-4-imidazolecarboxamide riboside in cardiac and skeletal muscle. Effects on purine nucleotide synthesis. J Biol Chem. 1982 Sep 10;257(17):10178–10183. [PubMed] [Google Scholar]
  19. Sabina R. L., Patterson D., Holmes E. W. 5-Amino-4-imidazolecarboxamide riboside (Z-riboside) metabolism in eukaryotic cells. J Biol Chem. 1985 May 25;260(10):6107–6114. [PubMed] [Google Scholar]
  20. Swain J. L., Hines J. J., Sabina R. L., Holmes E. W. Accelerated repletion of ATP and GTP pools in postischemic canine myocardium using a precursor of purine de novo synthesis. Circ Res. 1982 Jul;51(1):102–105. doi: 10.1161/01.res.51.1.102. [DOI] [PubMed] [Google Scholar]
  21. de Jong J. W., van der Meer P., van Loon H., Owen P., Opie L. H. Adenosine as adjunct to potassium cardioplegia: effect on function, energy metabolism, and electrophysiology. J Thorac Cardiovasc Surg. 1990 Sep;100(3):445–454. [PubMed] [Google Scholar]

Articles from British Heart Journal are provided here courtesy of BMJ Publishing Group

RESOURCES