Abstract
Thromboembolic phenomena involving the caval veins, right atrium, and pulmonary artery are recognised complications after the Fontan operation and other forms of total cavopulmonary connection. A rare case of systemic thromboembolism is reported in a 3 year old girl who had repeated coronary and cerebral thromboembolic events after a fenestrated total cavopulmonary shunt operation. A survey of the 18 paediatric cardiac units in the United Kingdom and Ireland showed a wide discrepancy in anticoagulation policies after Fontan-type operations. Prevention of thrombotic complications by lifelong postoperative anticoagulation may outweigh the risk of haemorrhage.
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- Bridges N. D., Lock J. E., Castaneda A. R. Baffle fenestration with subsequent transcatheter closure. Modification of the Fontan operation for patients at increased risk. Circulation. 1990 Nov;82(5):1681–1689. doi: 10.1161/01.cir.82.5.1681. [DOI] [PubMed] [Google Scholar]
- Cromme-Dijkhuis A. H., Henkens C. M., Bijleveld C. M., Hillege H. L., Bom V. J., van der Meer J. Coagulation factor abnormalities as possible thrombotic risk factors after Fontan operations. Lancet. 1990 Nov 3;336(8723):1087–1090. doi: 10.1016/0140-6736(90)92568-3. [DOI] [PubMed] [Google Scholar]
- DeLeon S. Y., Koopot R., Mair D. D., Idriss F. S., Ilbawi M. N., Muster A. J., Paul M. H. Surgical management of occluded conduits after the Fontan operation in patients with Glenn shunts. J Thorac Cardiovasc Surg. 1984 Oct;88(4):601–605. [PubMed] [Google Scholar]
- Dobell A. R., Trusler G. A., Smallhorn J. F., Williams W. G. Atrial thrombi after the Fontan operation. Ann Thorac Surg. 1986 Dec;42(6):664–667. doi: 10.1016/s0003-4975(10)64602-4. [DOI] [PubMed] [Google Scholar]
- Evans D. I., Rowlands M., Poller L. Survey of oral anticoagulant treatment in children. J Clin Pathol. 1992 Aug;45(8):707–708. doi: 10.1136/jcp.45.8.707. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Fontan F., Baudet E. Surgical repair of tricuspid atresia. Thorax. 1971 May;26(3):240–248. doi: 10.1136/thx.26.3.240. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Forfar J. C. Prediction of hemorrhage during long-term oral coumarin anticoagulation by excessive prothrombin ratio. Am Heart J. 1982 Mar;103(3):445–446. doi: 10.1016/0002-8703(82)90292-7. [DOI] [PubMed] [Google Scholar]
- Fyfe D. A., Kline C. H., Sade R. M., Gillette P. C. Transesophageal echocardiography detects thrombus formation not identified by transthoracic echocardiography after the Fontan operation. J Am Coll Cardiol. 1991 Dec;18(7):1733–1737. doi: 10.1016/0735-1097(91)90512-8. [DOI] [PubMed] [Google Scholar]
- Hedrick M., Elkins R. C., Knott-Craig C. J., Razook J. D. Successful thrombectomy for thrombosis of the right side of the heart after the Fontan operation. Report of two cases and review of the literature. J Thorac Cardiovasc Surg. 1993 Feb;105(2):297–301. [PubMed] [Google Scholar]
- Kirklin J. K., Blackstone E. H., Kirklin J. W., Pacifico A. D., Bargeron L. M., Jr The Fontan operation. Ventricular hypertrophy, age, and date of operation as risk factors. J Thorac Cardiovasc Surg. 1986 Dec;92(6):1049–1064. [PubMed] [Google Scholar]
- Turner-Gomes S. O., Andrew M., Coles J., Trusler G. A., Williams W. G., Rabinovitch M. Abnormalities in von Willebrand factor and antithrombin III after cardiopulmonary bypass operations for congenital heart disease. J Thorac Cardiovasc Surg. 1992 Jan;103(1):87–97. [PubMed] [Google Scholar]
- Turpie A. G., Gent M., Laupacis A., Latour Y., Gunstensen J., Basile F., Klimek M., Hirsh J. A comparison of aspirin with placebo in patients treated with warfarin after heart-valve replacement. N Engl J Med. 1993 Aug 19;329(8):524–529. doi: 10.1056/NEJM199308193290802. [DOI] [PubMed] [Google Scholar]

