Figure 2.
Inherent impulsive action predicts the DOI-elicited head-twitch response. Upon completion of 1-CSRT task training and phenotypic identification (cohort 1), injection of DOI (1 mg/kg, s.c.) resulted in head-twitches that were quantified over a 15-min period. (a) HI rats (n=7, black bar) exhibited a greater number of head twitches than LI rats (n=7, white bar; *p<0.05 vs LI-VEH). (b) There was a positive correlation between the number of head-twitches and premature responses during phenotype identification on the ITI8 challenge in the 1-CSRT task (r=0.499; p<0.01).