Abstract
Seventeen patient with sinoatrial block and 16 healthy volunteers were investigated with recently developed autonomic tests of atrial pacemaker function. Only one patients was found to be entirely normal in comparison with normal subjects, while another patients had supernormal responses. Fifteen patients had reduced responses relative to the controls implying impaired atrial pacemaker function or sinoatrial disease. It is suggested that while in some cases sinoatrial block may be of physiological origin, it is more often due to sinoatrial disease. The latter group are liable to Adams-Stokes syncope and may have additional atricventricular conduction abnormalities. The possible mechanisms and treatment of sinoatrial block are discussed relative to the autonomic and pacemaker function abnormalities described.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Dong E., Jr, Reitz B. A. Effect of timing of vagal stimulation on heart rate in the dog. Circ Res. 1970 Nov;27(5):635–646. doi: 10.1161/01.res.27.5.635. [DOI] [PubMed] [Google Scholar]
- Fielder D. L., Nelson D. C., Andersen T. W., Gravenstein J. S. Cardiovascular effects of atropine and neostigmine in man. Anesthesiology. 1969 Jun;30(6):637–641. doi: 10.1097/00000542-196906000-00013. [DOI] [PubMed] [Google Scholar]
- Mandel W., Hayakawa H., Danzig R., Marcus H. S. Evaluation of sino-atrial node function in man by overdrive suppression. Circulation. 1971 Jul;44(1):59–66. doi: 10.1161/01.cir.44.1.59. [DOI] [PubMed] [Google Scholar]
- Scherf D. The mechanism of sinoatrial block. Am J Cardiol. 1969 Jun;23(6):769–770. doi: 10.1016/0002-9149(69)90369-5. [DOI] [PubMed] [Google Scholar]