Abstract
Two patients with intractable life-threatening ventricular tachycardias have been studied using intracardiac electrograms and programmed electrical stimulation of the heart. Both patients have shown to have an underlying re-entry mechanism in the ventricles as the basis for the tachycardias. Both patients underwent epicardial mapping studies at cardiac surgery, and the site of re-entry was established. In one patient the re-entry front was found to start in the posterobasal region of the left ventricle and in the other patient the re-entry front was found in the anterobasal region of the right ventricle. In both patients surgical interruption of the re-entry front was carried out. Both patients are alive and free from tachycardias at the time of writing.
Full text
PDF











Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Cranefield P. F., Klein H. O., Hoffman B. F. Conduction of the cardiac impulse. 1. Delay, block, and one-way block in depressed Purkinje fibers. Circ Res. 1971 Feb;28(2):199–219. doi: 10.1161/01.res.28.2.199. [DOI] [PubMed] [Google Scholar]
- Durrer D., Roos J. P., van Dam R. T. The genesis of the electrocardiogram of patients with ostium primum defects (ventral atrial septal defects). Am Heart J. 1966 May;71(5):642–650. doi: 10.1016/0002-8703(66)90314-0. [DOI] [PubMed] [Google Scholar]
- Fontaine G., Frank R., Bonnet M., Cabrol C., Guiraudon G. Méthode d'étude expérimentale et clinique des syndromes de Wolff-Parkinson-White et d'ischémie myocardique par cartographie de la dépolarisation ventriculaire épicardique. Coeur Med Interne. 1973 Jan-Mar;12(1):105–113. [PubMed] [Google Scholar]
- Graham A. F., Miller D. C., Stinson E. B., Daily P. O., Fogarty T. J., Harrison D. C. Surgical treatment of refractory life-threatening ventricular tachycardia. Am J Cardiol. 1973 Dec;32(7):909–912. doi: 10.1016/s0002-9149(73)80156-0. [DOI] [PubMed] [Google Scholar]
- Han J., Goel B. G., Hanson C. S. Re-entrant beats induced in the ventricle during coronary occlusion. Am Heart J. 1970 Dec;80(6):778–784. doi: 10.1016/0002-8703(70)90139-0. [DOI] [PubMed] [Google Scholar]
- Nitter-Hauge S., Storstein O. Surgical treatment of recurrent ventricular tachycardia. Br Heart J. 1973 Nov;35(11):1132–1135. doi: 10.1136/hrt.35.11.1132. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Roos J. P., van Dam R. T., Durrer D. Epicardial and intramural excitation of normal heart in six patients 50 years of age and older. Br Heart J. 1968 Sep;30(5):630–637. doi: 10.1136/hrt.30.5.630. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Sasyniuk B. I., Mendez C. A mechanism for reentry in canine ventricualar tissue. Circ Res. 1971 Jan;28(1):3–15. doi: 10.1161/01.res.28.1.3. [DOI] [PubMed] [Google Scholar]
- Scherlag B. J., Lau S. H., Helfant R. H., Berkowitz W. D., Stein E., Damato A. N. Catheter technique for recording His bundle activity in man. Circulation. 1969 Jan;39(1):13–18. doi: 10.1161/01.cir.39.1.13. [DOI] [PubMed] [Google Scholar]
- Thind G. S., Blakemore W. S., Zinsser H. F. Ventricular aneurysmectomy for the treatment of recurrent ventricular tachyarrhythmia. Am J Cardiol. 1971 Jun;27(6):690–694. doi: 10.1016/0002-9149(71)90238-4. [DOI] [PubMed] [Google Scholar]
- Wallace A. G., Mignone R. J. Physiologic evidence concerning the re-entry hypothesis for ectopic beats. Am Heart J. 1966 Jul;72(1):60–70. doi: 10.1016/0002-8703(66)90628-4. [DOI] [PubMed] [Google Scholar]
- Wellens H. J., Schuilenburg R. M., Durrer D. Electrical stimulation of the heart in patients with ventricular tachycardia. Circulation. 1972 Aug;46(2):216–226. doi: 10.1161/01.cir.46.2.216. [DOI] [PubMed] [Google Scholar]







