Skip to main content
NCBI home page
British Heart Journal logoLink to British Heart Journal
. 1975 Feb;37(2):192–195. doi: 10.1136/hrt.37.2.192

Idiopathic giant cell myocarditis--a distinctive clinico-pathological entity.

M J Davies, A Pomerance, R D Teare
PMCID: PMC484100  PMID: 1122272

Abstract

Eleven cases of idiopathic giant cell myocarditis are described, The pathological features are unmistakable with serpiginous areas of myocardial necrosis, at the margins of which giant cells can be seen on histological examination. The aetiology of the condition remains obscure but associated pathology suggests that altered immunity may be a factor. The rapid clinical course is, however, highly suggestive of an infective cause though none has been found.

Full text

PDF
192

Images in this article

193Image
on p.193
194Image
on p.194

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Burke J. S., Medline N. M., Katz A. Giant cell myocarditis and myositis. Associated with thymoma and myasthenia gravis. Arch Pathol. 1969 Oct;88(4):359–366. [PubMed] [Google Scholar]
  2. DILLING N. V. Giant-cell myocarditis. J Pathol Bacteriol. 1956 Apr;71(2):295–300. doi: 10.1002/path.1700710204. [DOI] [PubMed] [Google Scholar]
  3. FUNKHOUSER J. W. Thymoma associated with myocarditis and the L.E.-cell phenomenon. Report of a case. N Engl J Med. 1961 Jan 5;264:34–36. doi: 10.1056/NEJM196101052640108. [DOI] [PubMed] [Google Scholar]
  4. Fleming H. A. Myocardial sarcoidosis. Lancet. 1973 Jan 13;1(7794):106–106. doi: 10.1016/s0140-6736(73)90507-2. [DOI] [PubMed] [Google Scholar]
  5. Gillie I., Fox H. Mitral stenosis together with a giant cell myocarditis limited to the left atrium. J Clin Pathol. 1968 Nov;21(6):750–752. doi: 10.1136/jcp.21.6.750. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. HUSBAND E. M., LANNIGAN R. UNUSUAL GIANT CELL LESIONS IN BIOPSY SPECIMEN OF LEFT ATRIAL APPENDAGES IN MITRAL STENOSIS. Br Heart J. 1965 Mar;27:269–273. doi: 10.1136/hrt.27.2.269. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Henry K. Striated muscle in human thymus. Lancet. 1968 Mar 23;1(7543):638–639. doi: 10.1016/s0140-6736(68)91262-2. [DOI] [PubMed] [Google Scholar]
  8. LANGSTON J. D., WAGMAN G. F., DICKENMAN R. C. Granulomatous myocarditis and myositis associated with thymoma. Arch Pathol. 1959 Oct;68:367–373. [PubMed] [Google Scholar]
  9. MCCREA P. C., CHILDERS R. W. TWO UNUSUAL CASES OF GIANT CELL MYOCARDITIS ASSOCIATED WITH MITRAL STENOSIS AND WITH WEGENER'S SYNDROME. Br Heart J. 1964 Jul;26:490–498. doi: 10.1136/hrt.26.4.490. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. PARRISH J. A. FIEDLER'S MYOCARDITIS. Br Heart J. 1965 May;27:458–461. doi: 10.1136/hrt.27.3.458. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. SABATINI D. D., BENSCH K., BARRNETT R. J. Cytochemistry and electron microscopy. The preservation of cellular ultrastructure and enzymatic activity by aldehyde fixation. J Cell Biol. 1963 Apr;17:19–58. doi: 10.1083/jcb.17.1.19. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. WALTON E. W. Giant-cell granuloma of the respiratory tract (Wegener's granulomatosis). Br Med J. 1958 Aug 2;2(5091):265–270. doi: 10.1136/bmj.2.5091.265. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. WHITEHEAD R. ISOLATED MYOCARDITIS. Br Heart J. 1965 Mar;27:220–230. doi: 10.1136/hrt.27.2.220. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from British Heart Journal are provided here courtesy of BMJ Publishing Group

RESOURCES