Correction: Middle East Respiratory Syndrome Coronavirus Intra-Host Populations Are Characterized by Numerous High Frequency Variants

In Table 1, the residue for 27162 should be 107, not 109. Please see the corrected Table 1 here.

Table 1. Nonsynonymous mutations occurring at >1% at sites with at least 100 X ORP coverage.

Nt pos.	Residue	Data type	SEED		C1D1		C1D3		C1D5		C2D1		C2D3		C2D5		C3D1		C3D3		C3D5		ORF
2169	I631L	Consensus	A	0.985	A	1.000	A	0.926	A	0.938	A	0.928	A	0.894	A	0.931	A	0.964	A	0.877	A	0.962	nsp2
		iSNV	C	0.015	NA		C	0.074	C	0.062	C	0.072	C	0.106	C	0.069	C	0.036	C	0.123	C	0.038
3475	K1066T	Consensus	A	1.000	A	1.000	A	1.000	A	1.000	A	1.000	A	1.000	A	0.992	A	1.000	A	1.000	A	0.804	nsp3
		iSNV	0		NA		NA		NA		0		NA		C	0.009	NA		0		C	0.197
6161	L1961V	Consensus	G	1.000	G	0.993	0		G	1.000	G	1.000	G	1.000	G	1.000	G	1.000	G	1.000	G	0.892
		iSNV	NA		T	0.008	NA		NA		NA		NA		NA		NA		NA		C	0.108
6172	F1965S	Consensus	T	0.858	C	0.583	0		C	0.812	C	0.938	C	0.939	C	0.955	C	0.921	C	1.000	C	1.000
		iSNV	C	0.142	T	0.417	NA		T	0.188	T	0.062	T	0.061	T	0.045	T	0.079	NA		NA
8050	D2591A	Consensus	A	0.941	A	1.000	A	1.000	A	1.000	A	0.622	A	0.998	A	0.994	A	0.912	A	0.923	A	0.922
		iSNV	C	0.060	NA		NA		NA		C	0.378	C	0.002	C	0.006	C	0.088	C	0.077	C	0.078
8614	M2779T	Consensus	T	1.000	0		0		T	0.942	T	0.845	0		0		T	0.951	T	1.000	T	0.850	nsp4
		iSNV	0		NA		NA		C	0.058	C	0.155	NA		NA		C	0.050	NA		C	0.150
9798	D3174H	Consensus	G	0.998	0		0		G	1.000	G	0.896	0		0		G	1.000	G	1.000	G	1.000
		iSNV	A	0.002	NA		NA		NA		C	0.104	NA		NA		NA		NA		NA
13234	E4319V	Consensus	A	1.000	0		0		A	1.000	A	1.000	0		0		A	0.855	A	1.000	A	0.940	nsp10
		iSNV	0		NA		NA		0		NA		NA		NA		T	0.145	NA		T	0.060
23150	E565D	Consensus	G	1.000	G	1.000	0		G	1.000	G	0.884	G	0.948	G	0.877	G	0.814	G	0.875	G	0.931	S gene
		iSNV	0		NA		NA		0		T	0.116	T	0.052	T	0.123	T	0.186	T	0.125	T	0.069
24474	A1007T	Consensus	G	1.000	0		0		G	0.986	G	0.721	G	1.000	G	0.969	G	0.820	G	0.821	G	0.889
		iSNV	NA		NA		NA		A	0.014	A	0.279	NA		A	0.031	A	0.180	A	0.179	A	0.111
24499	N1015T	Consensus	A	0.886	0		0		C	0.824	C	0.959	C	1.000	C	1.000	C	0.970	C	1.000	C	1.000
		iSNV	C	0.115	NA		NA		A	0.176	A	0.041	NA		NA		A	0.030	NA		NA
24502	N1016S	Consensus	A	0.986	0		0		A	0.967	A	1.000	A	1.000	A	1.000	A	0.956	A	1.000	A	0.978
		iSNV	G	0.014	NA		NA		G	0.033	NA		NA		NA		G	0.044	NA		G	0.022
24538	N1028S	Consensus	A	0.966	0		0		A	0.710	A	0.803	A	1.000	G	0.698	A	0.944	A	0.845	A	0.956
		iSNV	G	0.034	NA		NA		G	0.290	G	0.197	NA		A	0.302	G	0.056	G	0.155	G	0.044
27162	Y107*	Consensus	0		0		0		0		0		G	0.878	G	0.944	0		0		0		orf5
		iSNV	NA		NA		NA		NA		NA		A	0.122	A	0.056	NA		NA		NA
28464	R204S	Consensus	G	1.000	G	0.638	G	0.865	G	0.995	G	0.998	G	0.999	G	0.999	G	0.999	G	0.997	G	0.980	M gene
		iSNV	NA		T	0.362	T	0.100	T	0.005	T	0.001	T	0.001	T	0.001	T	0.001	T	0.002	T	0.020
28466	S2051	Consensus	G	0.999	G	1.000	G	0.920	G	0.996	G	0.997	G	0.999	G	0.999	G	0.998	G	0.997	G	0.965
		iSNV	NA		NA		T	0.080	T	0.004	T	0.002	T	0.001	T	0.001	T	0.002	T	0.002	T	0.025
28587	R8C	Consensus	C	0.993	C	0.996	C	0.993	C	0.990	C	0.996	C	0.950	C	0.996	C	1.000	C	1.000	C	1.000	N gene
		iSNV	T	0.007	A	0.004	T	0.007	T	0.010	T	0.004	T	0.050	T	0.004	NA		NA		NA
28778	L16P	Consensus	T	1.000	T	1.000	T	1.000	T	1.000	T	0.992	T	1.000	T	0.981	T	0.982	T	0.996	T	0.995
		iSNV	0		0		0		0		C	0.008	0		C	0.020	C	0.018	C	0.004	C	0.005
29734	G390V	Consensus	G	1.000	G	1.000	G	0.571	G	0.997	G	0.935	G	0.990	G	0.990	G	1.000	G	1.000	G	0.943
		iSNV	NA		NA		T	0.429	C	0.003	T	0.065	A	0.010	A	0.005	NA		NA		T	0.057
29737	S391I	Consensus	G	0.999	G	1.000	G	1.000	G	0.928	G	0.906	G	0.924	G	1.000	G	0.932	G	1.000	G	0.904
		iSNV	C	0.001	NA		NA		T	0.072	T	0.094	T	0.076	NA		T	0.063	NA		T	0.089
29747	Q394H	Consensus	G	0.992	0		G	1.000	G	0.985	G	0.936	G	0.800	G	1.000	G	0.992	G	0.876	G	0.911
		iSNV	A	0.008	NA		NA		NA		T	0.064	T	0.190	NA		A	0.008	T	0.124	T	0.073
29748	R395C	Consensus	C	0.950	0		C	1.000	C	0.994	C	0.973	C	1.000	C	1.000	C	0.940	C	0.955	C	0.998
		iSNV	T	0.050	NA		NA		A	0.006	T	0.027	NA		NA		T	0.058	T	0.045	G	0.002
29782	P406L	Consensus	C	1.000	0		0		0		C	1.000	C	1.000	C	1.000	T	1.000	C	1.000	C	0.787
		iSNV	0		NA		NA		NA		NA		NA		0		0		NA		T	0.213
29783	P406L	Consensus	A	1.000	0		0		0		A	1.000	A	1.000	A	1.000	G	1.000	A	1.000	A	0.787
		iSNV	0		NA		NA		NA		NA		NA		0		0		NA		G	0.213
29784	M407I	Consensus	A	1.000	0		0		0		A	1.000	A	1.000	A	1.000	T	1.000	A	1.000	A	0.787
		iSNV	0		NA		NA		NA		NA		NA		0		0		NA		T	0.213
29788	I408S	Consensus	T	1.000	0		0		0		T	1.000	T	1.000	T	1.000	T	1.000	T	1.000	T	0.858
		iSNV	NA		NA		NA		NA		NA		NA		NA		NA		NA		G	0.142
29794	V410S	Consensus	0		0.000		0.000		T	1.000	T	1.000	T	1.000	T	1.000	T	1.000	T	0.917	T	1.000
29794		iSNV	NA		NA		NA		NA		NA		NA		NA		NA		C	0.083	NA

There is an incorrect reference to Table 1 in the second sentence of the first paragraph the Results section, “ORF1ab.” The correct sentence is: The Seed stock had iSNVs present at nts 307–313, part of the nsp1 ORF (residues 9–11). All iSNVs were detected at 4% indicating there is a second genotype present at 4%.

The incorrect value reported in Table 1 also appears in the first sentence of the Results section, “ORF5.” The correct sentence is An iSNV resulting in a stop codon at residue 107 was detected in 12% of reads at nt 27162 for camel C2D5, the only sample for which there was adequate coverage at this site (>100x, S2 Table).