Fusion protein-selected antibodies recognize a 30 kDa Ae. aegypti salivary protein.
A. Mouse antibodies. Ae. aegypti saliva proteins were separated by SDS-PAGE and immunoblotted with mouse anti-saliva serum (lane 1), fusion protein-selected mouse antibodies (lane 2), or PBST (lane 3), followed by incubation with peroxidase-conjugated goat anti-mouse IgG.
B. Human antibodies. Ae. aegypti salivary proteins were separated by SDS-PAGE and immunoblotted with a pooled human mosquito-allergic serum (lane 1), fusion protein-selected human antibodies (lane 2), or PBST (lane 3), followed by incubation with mAb anti-human IgE.