Skip to main content
Heart logoLink to Heart
. 1996 Sep;76(3):274–279. doi: 10.1136/hrt.76.3.274

Long-term fate of the coronary arteries after the arterial switch operation in newborns with transposition of the great arteries.

D Bonnet 1, P Bonhoeffer 1, J F Piéchaud 1, Y Aggoun 1, D Sidi 1, C Planché 1, J Kachaner 1
PMCID: PMC484520  PMID: 8868989

Abstract

OBJECTIVE: Concern continues to be expressed about the long-term impact of coronary artery translocation after the arterial switch operation for transposition of the great arteries. This study was conducted to determine the prevalence of obstructions of the translocated coronary arteries by the use of selective coronary artery angiography. METHODS AND RESULTS: 64 children (mean age 7.6 (SD) 1.5 years) who had survived an arterial switch operation underwent evaluation. They had been operated on by one surgeon and they were followed up by a single hospital. Selective coronary artery angiography was possible in 58 patients. Five patients showed occlusion or stenosis of a coronary artery: one occlusion and two stenoses of the left coronary trunk, two occlusions of the circumflex artery. The prevalence of late coronary artery complications was 7.8 (SD) 6.6% (95% CI 1.2 to -14.4%). The three patients with occlusion of one coronary artery had perioperative ischaemic complications, with associated electrocardiogram evidence of ischaemia and left ventricular dysfunction with mitral valve insufficiency. Both patients with stenosis of the left main coronary artery trunk did not have any evidence of an anomaly before catheterisation. CONCLUSIONS: The prevalence of the late coronary artery complications after an arterial switch operation was low in this series. This accords with the view that the arterial switch operation remains the preferred treatment for such patients. Screening for late coronary artery patency should be done by using selective coronary artery angiography, because even patients who remain symptom free can have coronary artery anomalies.

Full text

PDF
274

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Arensman F. W., Sievers H. H., Lange P., Radley-Smith R., Bernhard A., Heintzen P., Yacoub M. H. Assessment of coronary and aortic anastomoses after anatomic correction of transposition of the great arteries. J Thorac Cardiovasc Surg. 1985 Oct;90(4):597–604. [PubMed] [Google Scholar]
  2. Bical O., Hazan E., Lecompte Y., Fermont L., Karam J., Jarreau M. M., Tran Viet T., Sidi D., Leca F., Neveux J. Y. Anatomic correction of transposition of the great arteries associated with ventricular septal defect: midterm results in 50 patients. Circulation. 1984 Nov;70(5):891–897. doi: 10.1161/01.cir.70.5.891. [DOI] [PubMed] [Google Scholar]
  3. Björkhem G., Evander E., White T., Lundström N. R. Myocardial scintigraphy with 201thallium in pediatric cardiology: a review of 52 cases. Pediatr Cardiol. 1990 Jan;11(1):1–7. doi: 10.1007/BF02239540. [DOI] [PubMed] [Google Scholar]
  4. Brutel de la Riviére A., Quaegebeur J. M., Hennis P. J., Bruteil de la Rivière G., Huysmans H. A., Brom A. G. Growth of an aorta-coronary anastomosis. An experimental study in pigs. J Thorac Cardiovasc Surg. 1983 Sep;86(3):393–399. [PubMed] [Google Scholar]
  5. Castaneda A. R., Norwood W. I., Jonas R. A., Colon S. D., Sanders S. P., Lang P. Transposition of the great arteries and intact ventricular septum: anatomical repair in the neonate. Ann Thorac Surg. 1984 Nov;38(5):438–443. doi: 10.1016/s0003-4975(10)64181-1. [DOI] [PubMed] [Google Scholar]
  6. Dae M. W. Myocardial perfusion after repair of transposition: is it worth the switch? J Am Coll Cardiol. 1994 Sep;24(3):778–779. doi: 10.1016/0735-1097(94)90028-0. [DOI] [PubMed] [Google Scholar]
  7. Day R. W., Laks H., Drinkwater D. C. The influence of coronary anatomy on the arterial switch operation in neonates. J Thorac Cardiovasc Surg. 1992 Sep;104(3):706–712. [PubMed] [Google Scholar]
  8. Hayes A. M., Baker E. J., Kakadeker A., Parsons J. M., Martin R. P., Radley-Smith R., Qureshi S. A., Yacoub M., Maisey M. N., Tynan M. Influence of anatomic correction for transposition of the great arteries on myocardial perfusion: radionuclide imaging with technetium-99m 2-methoxy isobutyl isonitrile. J Am Coll Cardiol. 1994 Sep;24(3):769–777. doi: 10.1016/0735-1097(94)90027-2. [DOI] [PubMed] [Google Scholar]
  9. Kirklin J. W., Blackstone E. H., Tchervenkov C. I., Castaneda A. R. Clinical outcomes after the arterial switch operation for transposition. Patient, support, procedural, and institutional risk factors. Congenital Heart Surgeons Society. Circulation. 1992 Nov;86(5):1501–1515. doi: 10.1161/01.cir.86.5.1501. [DOI] [PubMed] [Google Scholar]
  10. Marcus M. L., Chilian W. M., Kanatsuka H., Dellsperger K. C., Eastham C. L., Lamping K. G. Understanding the coronary circulation through studies at the microvascular level. Circulation. 1990 Jul;82(1):1–7. doi: 10.1161/01.cir.82.1.1. [DOI] [PubMed] [Google Scholar]
  11. Norwood W. I., Dobell A. R., Freed M. D., Kirklin J. W., Blackstone E. H. Intermediate results of the arterial switch repair. A 20-institution study. J Thorac Cardiovasc Surg. 1988 Dec;96(6):854–863. [PubMed] [Google Scholar]
  12. Paillole C., Sidi D., Kachaner J., Planché C., Belot J. P., Villain E., Le Bidois J., Piéchaud J. F., Pedroni E. Fate of pulmonary artery after anatomic correction of simple transposition of great arteries in newborn infants. Circulation. 1988 Oct;78(4):870–876. doi: 10.1161/01.cir.78.4.870. [DOI] [PubMed] [Google Scholar]
  13. Planché C., Bruniaux J., Lacour-Gayet F., Kachaner J., Binet J. P., Sidi D., Villain E. Switch operation for transposition of the great arteries in neonates. A study of 120 patients. J Thorac Cardiovasc Surg. 1988 Sep;96(3):354–363. [PubMed] [Google Scholar]
  14. Quaegebeur J. M., Rohmer J., Ottenkamp J., Buis T., Kirklin J. W., Blackstone E. H., Brom A. G. The arterial switch operation. An eight-year experience. J Thorac Cardiovasc Surg. 1986 Sep;92(3 Pt 1):361–384. [PubMed] [Google Scholar]
  15. Ralevic V., Burnstock G. Roles of P2-purinoceptors in the cardiovascular system. Circulation. 1991 Jul;84(1):1–14. doi: 10.1161/01.cir.84.1.1. [DOI] [PubMed] [Google Scholar]
  16. Serraf A., Lacour-Gayet F., Bruniaux J., Touchot A., Losay J., Comas J., Sousa Uva M., Planché C. Anatomic correction of transposition of the great arteries in neonates. J Am Coll Cardiol. 1993 Jul;22(1):193–200. doi: 10.1016/0735-1097(93)90834-n. [DOI] [PubMed] [Google Scholar]
  17. Sidi D., Planché C., Kachaner J., Bruniaux J., Villain E., le Bidois J., Piéchaud J. F., Lacour-Gayet F. Anatomic correction of simple transposition of the great arteries in 50 neonates. Circulation. 1987 Feb;75(2):429–435. doi: 10.1161/01.cir.75.2.429. [DOI] [PubMed] [Google Scholar]
  18. Tsuda E., Imakita M., Yagihara T., Ono Y., Echigo S., Takahashi O., Kamiya T. Late death after arterial switch operation for transposition of the great arteries. Am Heart J. 1992 Dec;124(6):1551–1557. doi: 10.1016/0002-8703(92)90071-3. [DOI] [PubMed] [Google Scholar]
  19. Weindling S. N., Wernovsky G., Colan S. D., Parker J. A., Boutin C., Mone S. M., Costello J., Castañeda A. R., Treves S. T. Myocardial perfusion, function and exercise tolerance after the arterial switch operation. J Am Coll Cardiol. 1994 Feb;23(2):424–433. doi: 10.1016/0735-1097(94)90430-8. [DOI] [PubMed] [Google Scholar]
  20. Wernovsky G., Hougen T. J., Walsh E. P., Sholler G. F., Colan S. D., Sanders S. P., Parness I. A., Keane J. F., Mayer J. E., Jonas R. A. Midterm results after the arterial switch operation for transposition of the great arteries with intact ventricular septum: clinical, hemodynamic, echocardiographic, and electrophysiologic data. Circulation. 1988 Jun;77(6):1333–1344. doi: 10.1161/01.cir.77.6.1333. [DOI] [PubMed] [Google Scholar]
  21. Yacoub M. H., Radley-Smith R. Anatomy of the coronary arteries in transposition of the great arteries and methods for their transfer in anatomical correction. Thorax. 1978 Aug;33(4):418–424. doi: 10.1136/thx.33.4.418. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Heart are provided here courtesy of BMJ Publishing Group

RESOURCES