Abstract
The case is presented of a patient with hypertrophic cardiomyopathy, midventricular obstruction, apical aneurysm, and very frequent episodes of sustained monomorphic ventricular tachycardia (VT) unresponsive to common antiarrhythmic drugs. Left ventricular catheter mapping during sinus rhythm suggested the presence of an extensively scarred apical region; early fractionated ECGs were recorded at the neck of the aneurysm during monomorphic VT, suggesting a possible role of this region as VT substrate. Radiofrequency delivery at these sites stopped the VT and it was no longer inducible; however, it spontaneously recurred the following day. An apical aneurysmectomy, guided by the results of catheter mapping, was performed and was successful in preventing arrhythmic recurrences during 12 months' follow up.
Full text
PDF


Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Alfonso F., Frenneaux M. P., McKenna W. J. Clinical sustained uniform ventricular tachycardia in hypertrophic cardiomyopathy: association with left ventricular apical aneurysm. Br Heart J. 1989 Feb;61(2):178–181. doi: 10.1136/hrt.61.2.178. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Barbier P., Bartorelli A. L. Doppler evidence of abnormal intracavitary systolic and diastolic flow in hypertrophic cardiomyopathy with midventricular obstruction. Am Heart J. 1993 Aug;126(2):483–487. doi: 10.1016/0002-8703(93)91081-o. [DOI] [PubMed] [Google Scholar]
- Fananapazir L., Chang A. C., Epstein S. E., McAreavey D. Prognostic determinants in hypertrophic cardiomyopathy. Prospective evaluation of a therapeutic strategy based on clinical, Holter, hemodynamic, and electrophysiological findings. Circulation. 1992 Sep;86(3):730–740. doi: 10.1161/01.cir.86.3.730. [DOI] [PubMed] [Google Scholar]
- Gilligan D. M., Missouris C. G., Boyd M. J., Oakley C. M. Sudden death due to ventricular tachycardia during amiodarone therapy in familial hypertrophic cardiomyopathy. Am J Cardiol. 1991 Oct 1;68(9):971–973. doi: 10.1016/0002-9149(91)90422-h. [DOI] [PubMed] [Google Scholar]
- Saumarez R. C., Camm A. J., Panagos A., Gill J. S., Stewart J. T., de Belder M. A., Simpson I. A., McKenna W. J. Ventricular fibrillation in hypertrophic cardiomyopathy is associated with increased fractionation of paced right ventricular electrograms. Circulation. 1992 Aug;86(2):467–474. doi: 10.1161/01.cir.86.2.467. [DOI] [PubMed] [Google Scholar]
- Webb J. G., Sasson Z., Rakowski H., Liu P., Wigle E. D. Apical hypertrophic cardiomyopathy: clinical follow-up and diagnostic correlates. J Am Coll Cardiol. 1990 Jan;15(1):83–90. doi: 10.1016/0735-1097(90)90180-w. [DOI] [PubMed] [Google Scholar]