Correction: Tauroursodeoxycholic Acid Mitigates High Fat Diet-Induced Cardiomyocyte Contractile and Intracellular Ca²⁺ Anomalies

The authors would like to correct Fig 6. In preparation of the figure for publication, the authors ran a representative gel for each of the experimental samples shown in panels A, B, C, and D of Fig 6. An α-Tubulin 52 KD loading control was then separately run and used as the representative loading control for all panels in Fig 6.

Fig 6. Levels of insulin signaling cascades in myocardium from low fat (LF) or high fat (HF)-fed C57 mice with or without TUDCA treatment (300 mg/kg for 15 days).

A: pIRS-1-to-IRS-1 ratio; B: pJNK-to-JNK ratio; C: pcJun-to-cJun ratio; and D: pERK-to-ERK ratio. Insets: Representative gel blots of total and phosphorylated IRS-1, JNK, cJun and ERK using specific antibodies. α-tubulin was used as the loading control. Mean±SEM; sample sizes are denoted in the bar graphs; *p<0.05 (two-way ANOVA).

The authors have provided a corrected version of Fig 6 here. The corrected Fig 6 shows the original, whole gels and their matching loading controls. Vertical black lines denote a rearrangement of bands from the raw gels. The authors confirm that these changes do not alter their findings and have provided raw, uncropped blots as Supporting Information.

Supporting Information

S1 File. Raw blots used to create the corrected version of Fig 6.

(PPT)