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Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1994 Oct;57(10):1228–1235. doi: 10.1136/jnnp.57.10.1228

Horizontal visual motion modulates focal attention in left unilateral spatial neglect.

J B Mattingley 1, J L Bradshaw 1, J A Bradshaw 1
PMCID: PMC485492  PMID: 7931385

Abstract

Patients with unilateral spatial neglect are impaired in directing focal attention toward the contralesional side of space. Provision of static spatial cues on the neglected side has previously been shown to help overcome this deficit. Common movement of visual stimuli may also guide the allocation of spatial attention, although such effects have not been examined in patients with unilateral spatial neglect. Eleven patients with right hemisphere damage and clinical evidence of left unilateral spatial neglect, and 11 matched, healthy controls were tested on a task of horizontal line bisection. Lines were presented on a computer display, with a neutral, static, or slowly drifting, random dot background. Under conditions of motion, background stimuli drifted either leftward or rightward, across the full width of the display, at speeds that did not elicit optokinetic nystagmus or perceptual aftereffects. Controls were accurate in all conditions, and showed minimal effects of background conditions. By contrast, patients with left unilateral spatial neglect were sensitive to leftward background motion, showing a significant leftward shift in bisection error, relative to neutral, static, and rightward moving backgrounds. There was no significant effect of rightward motion in comparison with the neutral and static conditions. The extent to which patients were susceptible to the effects of background motion was not related to severity of unilateral spatial neglect, as measured by clinical tests. The benefits of leftward motion may reflect activity of preserved motion processing mechanisms, which provide input to an otherwise dysfunctional attentional network. The use of visual motion to assist in contralesionally guiding focal attention may be useful in the rehabilitation of unilateral spatial neglect.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Albert M. L. A simple test of visual neglect. Neurology. 1973 Jun;23(6):658–664. doi: 10.1212/wnl.23.6.658. [DOI] [PubMed] [Google Scholar]
  2. Binder J., Marshall R., Lazar R., Benjamin J., Mohr J. P. Distinct syndromes of hemineglect. Arch Neurol. 1992 Nov;49(11):1187–1194. doi: 10.1001/archneur.1992.00530350109026. [DOI] [PubMed] [Google Scholar]
  3. Butter C. M., Mark V. W., Heilman K. M. An experimental analysis of factors underlying neglect in line bisection. J Neurol Neurosurg Psychiatry. 1988 Dec;51(12):1581–1583. doi: 10.1136/jnnp.51.12.1581. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. D'Erme P., Robertson I., Bartolomeo P., Daniele A., Gainotti G. Early rightwards orienting of attention on simple reaction time performance in patients with left-sided neglect. Neuropsychologia. 1992 Nov;30(11):989–1000. doi: 10.1016/0028-3932(92)90050-v. [DOI] [PubMed] [Google Scholar]
  5. Daffner K. R., Ahern G. L., Weintraub S., Mesulam M. M. Dissociated neglect behavior following sequential strokes in the right hemisphere. Ann Neurol. 1990 Jul;28(1):97–101. doi: 10.1002/ana.410280119. [DOI] [PubMed] [Google Scholar]
  6. De Renzi E., Gentilini M., Faglioni P., Barbieri C. Attentional shift towards the rightmost stimuli in patients with left visual neglect. Cortex. 1989 Jun;25(2):231–237. doi: 10.1016/s0010-9452(89)80039-5. [DOI] [PubMed] [Google Scholar]
  7. Driver J., Baylis G. C. Movement and visual attention: the spotlight metaphor breaks down. J Exp Psychol Hum Percept Perform. 1989 Aug;15(3):448–456. doi: 10.1037//0096-1523.15.3.448. [DOI] [PubMed] [Google Scholar]
  8. Gainotti G., D'Erme P., Bartolomeo P. Early orientation of attention toward the half space ipsilateral to the lesion in patients with unilateral brain damage. J Neurol Neurosurg Psychiatry. 1991 Dec;54(12):1082–1089. doi: 10.1136/jnnp.54.12.1082. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Halligan P. W., Marshall J. C. Figural modulation of visuo-spatial neglect: a case study. Neuropsychologia. 1991;29(7):619–628. doi: 10.1016/0028-3932(91)90097-r. [DOI] [PubMed] [Google Scholar]
  10. Halligan P. W., Marshall J. C. Homing in on neglect: a case study of visual search. Cortex. 1993 Mar;29(1):167–174. doi: 10.1016/s0010-9452(13)80222-5. [DOI] [PubMed] [Google Scholar]
  11. Halligan P. W., Marshall J. C. Homing in on neglect: a case study of visual search. Cortex. 1993 Mar;29(1):167–174. doi: 10.1016/s0010-9452(13)80222-5. [DOI] [PubMed] [Google Scholar]
  12. Halligan P. W., Marshall J. C. Left visuo-spatial neglect: a meaningless entity? Cortex. 1992 Dec;28(4):525–535. doi: 10.1016/s0010-9452(13)80225-0. [DOI] [PubMed] [Google Scholar]
  13. Hikosaka O., Miyauchi S., Shimojo S. Voluntary and stimulus-induced attention detected as motion sensation. Perception. 1993;22(5):517–526. doi: 10.1068/p220517. [DOI] [PubMed] [Google Scholar]
  14. Ishiai S., Furukawa T., Tsukagoshi H. Visuospatial processes of line bisection and the mechanisms underlying unilateral spatial neglect. Brain. 1989 Dec;112(Pt 6):1485–1502. doi: 10.1093/brain/112.6.1485. [DOI] [PubMed] [Google Scholar]
  15. Kaplan R. F., Verfaellie M., Meadows M. E., Caplan L. R., Pessin M. S., DeWitt L. D. Changing attentional demands in left hemispatial neglect. Arch Neurol. 1991 Dec;48(12):1263–1266. doi: 10.1001/archneur.1991.00530240067023. [DOI] [PubMed] [Google Scholar]
  16. Karnath H. O., Christ K., Hartje W. Decrease of contralateral neglect by neck muscle vibration and spatial orientation of trunk midline. Brain. 1993 Apr;116(Pt 2):383–396. doi: 10.1093/brain/116.2.383. [DOI] [PubMed] [Google Scholar]
  17. Làdavas E., Paladini R., Cubelli R. Implicit associative priming in a patient with left visual neglect. Neuropsychologia. 1993 Dec;31(12):1307–1320. doi: 10.1016/0028-3932(93)90100-e. [DOI] [PubMed] [Google Scholar]
  18. Mark V. W., Kooistra C. A., Heilman K. M. Hemispatial neglect affected by non-neglected stimuli. Neurology. 1988 Aug;38(8):1207–1211. doi: 10.1212/wnl.38.8.1207. [DOI] [PubMed] [Google Scholar]
  19. Marshall J. C., Halligan P. W. A study of plane bisection in four cases of visual neglect. Cortex. 1991 Jun;27(2):277–284. doi: 10.1016/s0010-9452(13)80132-3. [DOI] [PubMed] [Google Scholar]
  20. Marshall J. C., Halligan P. W. Blindsight and insight in visuo-spatial neglect. Nature. 1988 Dec 22;336(6201):766–767. doi: 10.1038/336766a0. [DOI] [PubMed] [Google Scholar]
  21. Mattingley J. B., Bradshaw J. L., Bradshaw J. A., Nettleton N. C. Residual rightward attentional bias after apparent recovery from right hemisphere damage: implications for a multicomponent model of neglect. J Neurol Neurosurg Psychiatry. 1994 May;57(5):597–604. doi: 10.1136/jnnp.57.5.597. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Mattingley J. B., Bradshaw J. L., Phillips J. G. Impairments of movement initiation and execution in unilateral neglect. Directional hypokinesia and bradykinesia. Brain. 1992 Dec;115(Pt 6):1849–1874. doi: 10.1093/brain/115.6.1849. [DOI] [PubMed] [Google Scholar]
  23. Mattingley J. B., Pierson J. M., Bradshaw J. L., Phillips J. G., Bradshaw J. A. To see or not to see: the effects of visible and invisible cues on line bisection judgements in unilateral neglect. Neuropsychologia. 1993 Nov;31(11):1201–1215. doi: 10.1016/0028-3932(93)90068-b. [DOI] [PubMed] [Google Scholar]
  24. McLeod P., Driver J., Crisp J. Visual search for a conjunction of movement and form is parallel. Nature. 1988 Mar 10;332(6160):154–155. doi: 10.1038/332154a0. [DOI] [PubMed] [Google Scholar]
  25. Mesulam M. M. Large-scale neurocognitive networks and distributed processing for attention, language, and memory. Ann Neurol. 1990 Nov;28(5):597–613. doi: 10.1002/ana.410280502. [DOI] [PubMed] [Google Scholar]
  26. Nichelli P., Rinaldi M., Cubelli R. Selective spatial attention and length representation in normal subjects and in patients with unilateral spatial neglect. Brain Cogn. 1989 Jan;9(1):57–70. doi: 10.1016/0278-2626(89)90044-4. [DOI] [PubMed] [Google Scholar]
  27. Patterson K., Bradshaw J. L. Differential hemispheric mediation of nonverbal visual stimuli. J Exp Psychol Hum Percept Perform. 1975 Aug;1(3):246–252. doi: 10.1037//0096-1523.1.3.246. [DOI] [PubMed] [Google Scholar]
  28. Pizzamiglio L., Frasca R., Guariglia C., Incoccia C., Antonucci G. Effect of optokinetic stimulation in patients with visual neglect. Cortex. 1990 Dec;26(4):535–540. doi: 10.1016/s0010-9452(13)80303-6. [DOI] [PubMed] [Google Scholar]
  29. Reuter-Lorenz P. A., Posner M. I. Components of neglect from right-hemisphere damage: an analysis of line bisection. Neuropsychologia. 1990;28(4):327–333. doi: 10.1016/0028-3932(90)90059-w. [DOI] [PubMed] [Google Scholar]
  30. Riddoch M. J., Humphreys G. W. The effect of cueing on unilateral neglect. Neuropsychologia. 1983;21(6):589–599. doi: 10.1016/0028-3932(83)90056-8. [DOI] [PubMed] [Google Scholar]
  31. Robertson I. Anomalies in the laterality of omissions in unilateral left visual neglect: implications for an attentional theory of neglect. Neuropsychologia. 1989;27(2):157–165. doi: 10.1016/0028-3932(89)90168-1. [DOI] [PubMed] [Google Scholar]
  32. Rubens A. B. Caloric stimulation and unilateral visual neglect. Neurology. 1985 Jul;35(7):1019–1024. doi: 10.1212/wnl.35.7.1019. [DOI] [PubMed] [Google Scholar]
  33. Schenkenberg T., Bradford D. C., Ajax E. T. Line bisection and unilateral visual neglect in patients with neurologic impairment. Neurology. 1980 May;30(5):509–517. doi: 10.1212/wnl.30.5.509. [DOI] [PubMed] [Google Scholar]
  34. Spinelli D., Zoccolotti P. Perception of moving and stationary gratings in brain damaged patients with unilateral spatial neglect. Neuropsychologia. 1992 Apr;30(4):393–401. doi: 10.1016/0028-3932(92)90112-y. [DOI] [PubMed] [Google Scholar]
  35. Tegnér R., Levander M., Caneman G. Apparent right neglect in patients with left visual neglect. Cortex. 1990 Sep;26(3):455–458. doi: 10.1016/s0010-9452(13)80095-0. [DOI] [PubMed] [Google Scholar]
  36. Tegnér R., Levander M. The influence of stimulus properties on visual neglect. J Neurol Neurosurg Psychiatry. 1991 Oct;54(10):882–887. doi: 10.1136/jnnp.54.10.882. [DOI] [PMC free article] [PubMed] [Google Scholar]
  37. Theeuwes J. Visual selective attention: a theoretical analysis. Acta Psychol (Amst) 1993 Jun;83(2):93–154. doi: 10.1016/0001-6918(93)90042-p. [DOI] [PubMed] [Google Scholar]
  38. Vallar G., Bottini G., Rusconi M. L., Sterzi R. Exploring somatosensory hemineglect by vestibular stimulation. Brain. 1993 Feb;116(Pt 1):71–86. doi: 10.1093/brain/116.1.71. [DOI] [PubMed] [Google Scholar]
  39. Weintraub S., Mesulam M. M. Right cerebral dominance in spatial attention. Further evidence based on ipsilateral neglect. Arch Neurol. 1987 Jun;44(6):621–625. doi: 10.1001/archneur.1987.00520180043014. [DOI] [PubMed] [Google Scholar]

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