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Serum dolutegravir levels pre and postdose in 1st trimester (13 weeks of gestation) and 3rd trimester (32 weeks of gestation).
DTG = dolutegravir, q.d. = once-daily, b.i.d. = twice-daily, IC90 = inhibitory concentration for 90% of viral growth. Dolutegravir concentrations were measured by liquid chromatography with tandem mass spectrometry after resolving the glucuronidated dolutegravir from parent compound.
