Table 2.
Treatment duration and responses.
| Patient no. | Duration of Rx A⁎ | Best response to Rx A⁎ | Duration oral maintenance⁎⁎ | PFS | Additional treatment | Status as of Feb. 2016 | OS |
|---|---|---|---|---|---|---|---|
| 1 | 3 months (stopped on request) | Very good partial response (VGPR) | 5 months | 7 months | EBRT to eye; doxorubicin; gemcitabine + cisplatin | Died of PD Oct. 2012 | 14 months |
| 2 | 12 months | Complete clinical response. MRI still showed some diffuse scalp thickening: VGPR. | 12 months | 24 months | EBRT to scalp | Died of PD Oct. 2014 | 30 months |
| 3 | 12 months | Complete clinical & metabolic response | 2 months | 14 months | EBRT to scalp, bones; paclitaxel; thalidomide | Died of PD Mar. 2015 | 19 months |
| 4 | 4 months (could not continue due to low platelet counts) | Bone marrow complete morphological response | Could not take much chemo due to autoimmune thrombo-cytopenia | 5 months | EBRT to bones; thalidomide | Died of PD Aug. 2014 | 10 months |
| 5 | 11 months | Complete response of residual lung nodules | 3 months | 11 months | Palliative care | Died of progresive disease Apr. 2015 | 16 months |
| 6 | 12 months | Very good partial response (VGPR) | 3 months | 19 + months | N/A | Alive on Rx with VGPR |
19 + months |
| 7 | 5 months (stopped due to logistics) | Partial response | Not started | 14 + months | Presently on thalidomide/oral etoposide | Alive on Rx with stable disease | 14 + months |
EBRT: external beam radio therapy; PD: progressive disease.
⁎
Rx A: Propranolol /Vinblastine/Methotrexate.
⁎⁎
Maintenance Rx: oral etoposide/cyclophosphamide/propranolol.