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. 1996 Jan;60(1):87–90. doi: 10.1136/jnnp.60.1.87

Inflammatory demyelinating polyradiculitis in a patient with acute disseminated encephalomyelitis (ADEM).

A Kinoshita 1, M Hayashi 1, K Miyamoto 1, M Oda 1, H Tanabe 1
PMCID: PMC486196  PMID: 8558159

Abstract

A patient with severe acute disseminated encephalomyelitis died 12 days after the first symptom. Necropsy showed widespread severe demyelination in the CNS and some foci of demyelination in the spinal roots. The lesions in the peripheral nervous system were characterised by myelin stripping and the presence of macrophages, being severest in the spinal nerve roots. Some axons were completely demyelinated, whereas the axons themselves were preserved. Pathologically established ongoing demyelination in both CNS and peripheral nervous systems raises the possibility of a shared pathological epitope.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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