Table 1. Clinical and biological characteristics of CLL cases.

Variable	Category	CLL cases (n = 80)
Age at diagnosis
	Median (range)	58.7 (37-80)
Gender (F/M)
	Female	22 (27.5%)
	Male	58 (72.5%)
Percentage of tumor cells
	Median (range)	97 (64-99)
Rai stage
	0	38 (47.50%)
	I	12 (15%)
	II	18 (22.5%)
	III	5 (6.25%)
	IV	7 (8.75%)
Binet stage
	A	51 (63.75%)
	B	18 (22.5%)
	C	11 (13.75%)
Previous treatment
	Untreated	68 (85%)
	Treated	12 (15%)
IGVH status
	Mutated	46 (57.5%)
	Unmutated	33 (41.25%)
	Not evaluated	1 (1.25%)
ZAP-70 expression
	ZAP-70−	57 (71.25%)
	ZAP-70+	22 (27.5%)
	Not evaluated	1 (1.25%)
CD38 expression
	CD38−	61 (76.25%)
	CD38+	18 (22.5%)
	Not evaluated	1 (1.25%)
CD49d expression
	CD49d−	15 (18.75%)
	CD49d+	46 (57.5%)
	Not evaluated	19 (23.75%)
Cytogenetics
	Deletion of 17p	2 (2.5%)
	Trisomy 12	8 (10%)
	Deletion of 13q	44 (55%)
	Deletion of 11q	10 (12.5%)
	Normal	20 (25%)
	Not evaluated	1 (1.25%)
Recurrent mutations
	ATM	7 (8.75%)
	SF3B1	5 (6.25%)
	NOTCH1	4 (5%)
	MYD88	2 (2.5%)
	TP53	4 (5%)