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. 1970 Jul;32(4):537–546. doi: 10.1136/hrt.32.4.537

Natural history of ventricular septal defect with right-sided aortic arch1

P J Varghese 1, J R Allen 1, G C Rosenquist 1, R D Rowe 1
PMCID: PMC487366  PMID: 5433315

Abstract

The natural history of 14 patients with ventricular septal defect and right-sided aortic arch is reviewed. Patients are divided into two groups. Group A consisted of 10 patients, all of whom developed progressive infundibular stenosis; group B consisted of 4 patients, none of whom developed infundibular stenosis. The clinical features, x-rays, electrocardiograms, haemodynamic data, and angiocardiograms in these two groups are compared.

The right ventricular cine-angiocardiogram seems to be helpful in differentiating the course of the two groups. The patients who developed progressive infundibular stenosis showed an abnormal right ventricular cine-angiocardiogram even in the absence of obstruction. Various aetiological factors for the development of infundibular stenosis are discussed.

The importance of medical management in group A patients is emphasized, even though all of them presented in infancy in congestive heart failure. The role of propranolol in preventing cyanotic spells in group A patients is also discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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