Abstract
A 39-year-old man with aortic stenosis and regurgitation developed Q fever endocarditis. After 15 weeks of chemotherapy with tetracycline the damaged aortic valve was replaced with a homograft. Organisms were present in the excised valve. Some months later the valve began to leak and the endocarditis recurred fatally. Because of the nature of rickettsial infection neither a course of chemotherapy nor an operation can guarantee a cure of Q fever endocarditis. Chemotherapy should be continued indefinitely even after operation.
Full text
PDFImages in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Braniff B. A., Shumway N. E., Harrison D. C. Valve replacement in active bacterial endocarditis. N Engl J Med. 1967 Jun 29;276(26):1464–1467. doi: 10.1056/NEJM196706292762604. [DOI] [PubMed] [Google Scholar]
- Kristinsson A., Bentall H. H. Medical and surgical treatment of Q-fever endocarditis. Lancet. 1967 Sep 30;2(7518):693–697. doi: 10.1016/s0140-6736(67)90975-0. [DOI] [PubMed] [Google Scholar]
- MARMION B. P., STOKER M. G. The epidemiology of Q fever in Great Britain; an analysis of the findings and some conclusions. Br Med J. 1958 Oct 4;2(5100):809–816. doi: 10.1136/bmj.2.5100.809. [DOI] [PMC free article] [PubMed] [Google Scholar]
- McDonald A., McDonald L., Resnekov L., Robinson M., Ross D. Homograft replacement of the aortic valve. Immediate results and follow-up. Lancet. 1968 Aug 31;2(7566):469–474. doi: 10.1016/s0140-6736(68)90645-4. [DOI] [PubMed] [Google Scholar]
- Morgans C. M., Cartwright R. Y. Case of Q fever endocarditis at site of aortic valve prosthesis. Br Heart J. 1969 Jul;31(4):520–522. doi: 10.1136/hrt.31.4.520. [DOI] [PMC free article] [PubMed] [Google Scholar]
- PRICE W. H., EMERSON H., NAGEL H., BLUMBERG R., TALMADGE S. Ecologic studies on the interepidemic survival of louse-borne epidemic typhus fever. Am J Hyg. 1958 Mar;67(2):154–178. doi: 10.1093/oxfordjournals.aje.a119925. [DOI] [PubMed] [Google Scholar]