Table 1.

Metabolic parameters of 14- and 24-week-old male WT and ΔF508 mutant mice

	14 weeks old		24 weeks old
	WT	ΔF508	WT	ΔF508
Insulin (pmol/L)	141 ± 27	88 ± 24	205 ± 26	134 ± 21
Glucagon (ng/L)	315 ± 32	398 ± 30	340 ± 32	268 ± 19
TG (mmol/L)	11.9 ± 1.9	5.1 ± 0.7***	9.6 ± 1.5	7.5 ± 1.3
Total cholesterol (mmol/L)	1.84 ± 0.23	1.11 ± 0.28*	2.10 ± 0.15	2.05 ± 0.80

Data are means ± SEM of 4–17 mice.

*P < 0.05,

***P < 0.001 vs. WT mice.