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. Author manuscript; available in PMC: 2016 May 24.
Published in final edited form as: Epilepsia. 2012 Nov 28;54(4):596–604. doi: 10.1111/epi.12041

Figure 4.

Figure 4

EEG-behavioral correlates of ictal events induced by systemic 4AP administration. Representative EEG recordings of a nonconvulsive (A) and a convulsive seizure (B) in the ipsilateral CA3 and EC, with corresponding behavioral symptoms. Arrows indicate seizure-onset time. In A, automatisms and an increase of exploratory behaviors occurred during the nonconvulsive seizure after onset in EC, whereas head and trunk extension occurred when the epileptiform activity was also observed in the ipsilateral CA3. Panel B shows a convulsive seizure with a tonic phase, characterized by head and trunk extension, followed by a tonic–clonic phase, characterized by a head and trunk extension associated with rearing and falling. Both the tonic and the tonic–clonic phase were associated to epileptiform activity in both CA3 and EC. Both seizure types were followed by wet-dog shakes (WDS).