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(A) Arterial ring from swine with mild CAD, interrogated with an antibody against Ki-67. (B) Arterial ring from swine with severe CAD, interrogated with an antibody against Ki-67. (C–D) Zoomed-in regions of rings in panels A and B. Black arrows indicate positive Ki-67 staining. Diamond arrows indicate negative Ki-67 stain. (E) Ki-67 expression is decreased in severe CAD. (Mild CAD = 8 pigs; Severe CAD = 5 pigs).
