Abstract
A non-invasive technique for quantification of argon laser induced burning second pain (C-fibre) is suggested. Using frequency analysis event related responses to burning pain can be detected in the EEG interval 1-2 seconds after laser stimulation. When the laser stimulus induced a burning pain perception, the power from 0.5-2.5 Hz of the EEG interval 1-2 seconds after stimulation differed significantly from the power calculated from the same time interval when no burning pain was perceived.
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Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Angel R. W., Quick W. M., Boylls C. C., Weinrich M., Rodnitzky R. L. Decrement of somatosensory evoked potentials during repetitive stimulation. Electroencephalogr Clin Neurophysiol. 1985 Apr;60(4):335–342. doi: 10.1016/0013-4694(85)90007-0. [DOI] [PubMed] [Google Scholar]
- Arendt-Nielsen L., Bjerring P. Reaction times to painless and painful CO2 and argon laser stimulation. Eur J Appl Physiol Occup Physiol. 1988;58(3):266–273. doi: 10.1007/BF00417261. [DOI] [PubMed] [Google Scholar]
- Arendt-Nielsen L., Bjerring P. Selective averaging of argon laser induced pre-pain and pain related cortical responses. J Neurosci Methods. 1988 Jun;24(2):117–123. doi: 10.1016/0165-0270(88)90054-4. [DOI] [PubMed] [Google Scholar]
- Arendt-Nielsen L., Bjerring P. Sensory and pain threshold characteristics to laser stimuli. J Neurol Neurosurg Psychiatry. 1988 Jan;51(1):35–42. doi: 10.1136/jnnp.51.1.35. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Arendt-Nielsen L. First pain event related potentials to argon laser stimuli: recording and quantification. J Neurol Neurosurg Psychiatry. 1990 May;53(5):398–404. doi: 10.1136/jnnp.53.5.398. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Bjerring P., Arendt-Nielsen L. Argon laser induced single cortical responses: a new method to quantify pre-pain and pain perceptions. J Neurol Neurosurg Psychiatry. 1988 Jan;51(1):43–49. doi: 10.1136/jnnp.51.1.43. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Bromm B., Treede R. D. Human cerebral potentials evoked by CO2 laser stimuli causing pain. Exp Brain Res. 1987;67(1):153–162. doi: 10.1007/BF00269463. [DOI] [PubMed] [Google Scholar]
- Bromm B., Treede R. D. Nerve fibre discharges, cerebral potentials and sensations induced by CO2 laser stimulation. Hum Neurobiol. 1984;3(1):33–40. [PubMed] [Google Scholar]
- Carmon A. Considerations of the cerebral response to painful stimulation: stimulus transduction versus perceptual event. Bull N Y Acad Med. 1979 Mar;55(3):313–324. [PMC free article] [PubMed] [Google Scholar]
- Carmon A., Dotan Y., Sarne Y. Correlation of subjective pain experience with cerebral evoked responses to noxious thermal stimulations. Exp Brain Res. 1978 Nov 15;33(3-4):445–453. doi: 10.1007/BF00235566. [DOI] [PubMed] [Google Scholar]
- Carmon A., Friedman Y., Coger R., Kenton B. Single trial analysis of evoked potentials to noxious thermal stimulation in man. Pain. 1980 Feb;8(1):21–32. doi: 10.1016/0304-3959(80)90087-1. [DOI] [PubMed] [Google Scholar]
- Carmon A., Mor J., Goldberg J. Evoked cerebral responses to noxious thermal stimuli in humans. Exp Brain Res. 1976 May 10;25(1):103–107. doi: 10.1007/BF00237330. [DOI] [PubMed] [Google Scholar]
- Coger R. W., Kenton B., Pinsky J. J., Crue B. L., Carmon A., Friedman Y. Somatosensory evoked potentials and noxious stimulation in patients with intractable, noncancer pain syndromes. Psychiatry Res. 1980 Jul;2(3):279–294. doi: 10.1016/0165-1781(80)90020-7. [DOI] [PubMed] [Google Scholar]
- Haimi-Cohen R., Cohen A., Carmon A. A model for the temperature distribution in skin noxiously stimulated by a brief pulse of CO2 laser radiation. J Neurosci Methods. 1983 Jun;8(2):127–137. doi: 10.1016/0165-0270(83)90113-9. [DOI] [PubMed] [Google Scholar]
- Jacobson R. C., Chapman C. R., Gerlach R. Stimulus intensity and inter-stimulus interval effects on pain-related cerebral potentials. Electroencephalogr Clin Neurophysiol. 1985 Sep;62(5):352–363. doi: 10.1016/0168-5597(85)90044-9. [DOI] [PubMed] [Google Scholar]
- Katz S., Martin H. F., Blackburn J. G. The effects of interaction between large and small diameter fiber systems on the somatosensory evoked potential. Electroencephalogr Clin Neurophysiol. 1978 Jul;45(1):45–52. doi: 10.1016/0013-4694(78)90340-1. [DOI] [PubMed] [Google Scholar]
- Kenton B., Coger R., Crue B., Pinsky J., Friedman Y., Carmon A. Peripheral fiber correlates to noxious thermal stimulation in humans. Neurosci Lett. 1980 May 1;17(3):301–306. doi: 10.1016/0304-3940(80)90040-3. [DOI] [PubMed] [Google Scholar]
- Schafer E. W., Amochaev A., Russell M. J. Knowledge of stimulus timing attenuates human evoked cortical potentials. Electroencephalogr Clin Neurophysiol. 1981 Jul;52(1):9–17. doi: 10.1016/0013-4694(81)90183-8. [DOI] [PubMed] [Google Scholar]
- Stowell H. Event related brain potentials and human pain: a first objective overview. Int J Psychophysiol. 1984 Feb;1(2):137–151. doi: 10.1016/0167-8760(84)90034-5. [DOI] [PubMed] [Google Scholar]
- Treede R. D., Kief S., Hölzer T., Bromm B. Late somatosensory evoked cerebral potentials in response to cutaneous heat stimuli. Electroencephalogr Clin Neurophysiol. 1988 Nov;70(5):429–441. doi: 10.1016/0013-4694(88)90020-x. [DOI] [PubMed] [Google Scholar]
- Van Hees J., Gybels J. C nociceptor activity in human nerve during painful and non painful skin stimulation. J Neurol Neurosurg Psychiatry. 1981 Jul;44(7):600–607. doi: 10.1136/jnnp.44.7.600. [DOI] [PMC free article] [PubMed] [Google Scholar]