Abstract
A 79 year old man with a twelve year progressive history of prosopagnosia and recent naming difficulty, in whom other intellectual skills were preserved, is described. Positron emission tomography (PET) revealed an area of right temporal lobe hypometabolism, with an additional area of less severe hypometabolism at the left temporal pole. This may represent an example of progressive focal cortical degeneration similar to that associated with primary progressive dysphasia, but affecting the right temporal lobe.
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- Benson D. F., Davis R. J., Snyder B. D. Posterior cortical atrophy. Arch Neurol. 1988 Jul;45(7):789–793. doi: 10.1001/archneur.1988.00520310107024. [DOI] [PubMed] [Google Scholar]
- Bruce V., Young A. Understanding face recognition. Br J Psychol. 1986 Aug;77(Pt 3):305–327. doi: 10.1111/j.2044-8295.1986.tb02199.x. [DOI] [PubMed] [Google Scholar]
- Chawluk J. B., Mesulam M. M., Hurtig H., Kushner M., Weintraub S., Saykin A., Rubin N., Alavi A., Reivich M. Slowly progressive aphasia without generalized dementia: studies with positron emission tomography. Ann Neurol. 1986 Jan;19(1):68–74. doi: 10.1002/ana.410190112. [DOI] [PubMed] [Google Scholar]
- Coughlan A. K., Warrington E. K. Word-comprehension and word-retrieval in patients with localized cerebral lesions. Brain. 1978 Mar;101(1):163–185. doi: 10.1093/brain/101.1.163. [DOI] [PubMed] [Google Scholar]
- Damasio A. R., Damasio H., Van Hoesen G. W. Prosopagnosia: anatomic basis and behavioral mechanisms. Neurology. 1982 Apr;32(4):331–341. doi: 10.1212/wnl.32.4.331. [DOI] [PubMed] [Google Scholar]
- De Renzi E. Prosopagnosia in two patients with CT scan evidence of damage confined to the right hemisphere. Neuropsychologia. 1986;24(3):385–389. doi: 10.1016/0028-3932(86)90023-0. [DOI] [PubMed] [Google Scholar]
- De Renzi E. Slowly progressive visual agnosia or apraxia without dementia. Cortex. 1986 Mar;22(1):171–180. doi: 10.1016/s0010-9452(86)80041-7. [DOI] [PubMed] [Google Scholar]
- Faden A. I., Townsend J. J. Myoclonus in Alzheimer disease. A confusing sign. Arch Neurol. 1976 Apr;33(4):278–280. doi: 10.1001/archneur.1976.00500040062010. [DOI] [PubMed] [Google Scholar]
- Folstein M. F., Folstein S. E., McHugh P. R. "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975 Nov;12(3):189–198. doi: 10.1016/0022-3956(75)90026-6. [DOI] [PubMed] [Google Scholar]
- Frackowiak R. S., Lenzi G. L., Jones T., Heather J. D. Quantitative measurement of regional cerebral blood flow and oxygen metabolism in man using 15O and positron emission tomography: theory, procedure, and normal values. J Comput Assist Tomogr. 1980 Dec;4(6):727–736. doi: 10.1097/00004728-198012000-00001. [DOI] [PubMed] [Google Scholar]
- Frackowiak R. S., Pozzilli C., Legg N. J., Du Boulay G. H., Marshall J., Lenzi G. L., Jones T. Regional cerebral oxygen supply and utilization in dementia. A clinical and physiological study with oxygen-15 and positron tomography. Brain. 1981 Dec;104(Pt 4):753–778. doi: 10.1093/brain/104.4.753. [DOI] [PubMed] [Google Scholar]
- Kertesz A., Harlock W., Coates R. Computer tomographic localization, lesion size, and prognosis in aphasia and nonverbal impairment. Brain Lang. 1979 Jul;8(1):34–50. doi: 10.1016/0093-934x(79)90038-5. [DOI] [PubMed] [Google Scholar]
- Kirshner H. S., Tanridag O., Thurman L., Whetsell W. O., Jr Progressive aphasia without dementia: two cases with focal spongiform degeneration. Ann Neurol. 1987 Oct;22(4):527–532. doi: 10.1002/ana.410220413. [DOI] [PubMed] [Google Scholar]
- Lammertsma A. A., Jones T. Correction for the presence of intravascular oxygen-15 in the steady-state technique for measuring regional oxygen extraction ratio in the brain: 1. Description of the method. J Cereb Blood Flow Metab. 1983 Dec;3(4):416–424. doi: 10.1038/jcbfm.1983.67. [DOI] [PubMed] [Google Scholar]
- Lammertsma A. A., Wise R. J., Heather J. D., Gibbs J. M., Leenders K. L., Frackowiak R. S., Rhodes C. G., Jones T. Correction for the presence of intravascular oxygen-15 in the steady-state technique for measuring regional oxygen extraction ratio in the brain: 2. Results in normal subjects and brain tumour and stroke patients. J Cereb Blood Flow Metab. 1983 Dec;3(4):425–431. doi: 10.1038/jcbfm.1983.68. [DOI] [PubMed] [Google Scholar]
- Landis T., Regard M., Bliestle A., Kleihues P. Prosopagnosia and agnosia for noncanonical views. An autopsied case. Brain. 1988 Dec;111(Pt 6):1287–1297. doi: 10.1093/brain/111.6.1287. [DOI] [PubMed] [Google Scholar]
- Mandell A. M., Alexander M. P., Carpenter S. Creutzfeldt-Jakob disease presenting as isolated aphasia. Neurology. 1989 Jan;39(1):55–58. doi: 10.1212/wnl.39.1.55. [DOI] [PubMed] [Google Scholar]
- Mesulam M. M. Slowly progressive aphasia without generalized dementia. Ann Neurol. 1982 Jun;11(6):592–598. doi: 10.1002/ana.410110607. [DOI] [PubMed] [Google Scholar]
- Poeck K., Luzzatti C. Slowly progressive aphasia in three patients. The problem of accompanying neuropsychological deficit. Brain. 1988 Feb;111(Pt 1):151–168. doi: 10.1093/brain/111.1.151. [DOI] [PubMed] [Google Scholar]
- Pogacar S., Williams R. S. Alzheimer's disease presenting as slowly progressive aphasia. R I Med J. 1984 Apr;67(4):181–185. [PubMed] [Google Scholar]
- Warrington E. K., James M. Visual apperceptive agnosia: a clinico-anatomical study of three cases. Cortex. 1988 Mar;24(1):13–32. doi: 10.1016/s0010-9452(88)80014-5. [DOI] [PubMed] [Google Scholar]
- Warrington E. K., McCarthy R. A. The fractionation of retrograde amnesia. Brain Cogn. 1988 Apr;7(2):184–200. doi: 10.1016/0278-2626(88)90029-2. [DOI] [PubMed] [Google Scholar]
- Wechsler A. F. Presenile dementia presenting as aphasia. J Neurol Neurosurg Psychiatry. 1977 Mar;40(3):303–305. doi: 10.1136/jnnp.40.3.303. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Wechsler A. F., Verity M. A., Rosenschein S., Fried I., Scheibel A. B. Pick's disease. A clinical, computed tomographic, and histologic study with golgi impregnation observations. Arch Neurol. 1982 May;39(5):287–290. doi: 10.1001/archneur.1982.00510170029008. [DOI] [PubMed] [Google Scholar]
- Whiteley A. M., Warrington E. K. Prosopagnosia: a clinical, psychological, and anatomical study of three patients. J Neurol Neurosurg Psychiatry. 1977 Apr;40(4):395–403. doi: 10.1136/jnnp.40.4.395. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Yamanouchi H., Budka H., Vass K., Sr Unilateral Creutzfeldt-Jakob disease. Neurology. 1986 Nov;36(11):1517–1520. doi: 10.1212/wnl.36.11.1517. [DOI] [PubMed] [Google Scholar]