Skip to main content
NCBI home page
Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1991 Apr;54(4):288–292. doi: 10.1136/jnnp.54.4.288

Destructive lesions in demyelinating disease.

B D Youl 1, A G Kermode 1, A J Thompson 1, T Révész 1, F Scaravilli 1, R O Barnard 1, F J Kirkham 1, B E Kendall 1, D Kingsley 1, I F Moseley 1, et al.
PMCID: PMC488480  PMID: 2056314

Abstract

Three cases are presented in which clinical and radiological features suggested the diagnosis of glioma but surgical biopsy revealed a demyelinating process, with tissue destruction and cyst formation in two. One patient had clinically definite multiple sclerosis. Two had probable acute disseminated encephalomyelitis. Treatment with high dose steroids is appropriate when there is clinical or investigative evidence to suggest the presence of demyelinating disease, before deciding on biopsy.

Full text

PDF
288

Images in this article

289Image
on p.289
290Image
on p.290
290Image
on p.290
291Image
on p.291

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ADAMS R. D., KUBIK C. S. The morbid anatomy of the demyelinative disease. Am J Med. 1952 May;12(5):510–546. doi: 10.1016/0002-9343(52)90234-9. [DOI] [PubMed] [Google Scholar]
  2. Harpey J. P., Renault F., Foncin J. F., Gardeur D., Horn Y. E., Roy C. Démyélinisation aiguë pseudotumorale à poussées régressives. Arch Fr Pediatr. 1983 May;40(5):407–409. [PubMed] [Google Scholar]
  3. Howell D. A., Jellinek E. H., Gavrilescu K. Demyelinating disease in a woman from tropical South America with features of multiple sclerosis and neuromyelitis optica. Clinical, protein chemistry and pathological findings. J Neurol Sci. 1968 Jul-Aug;7(1):115–135. doi: 10.1016/0022-510x(68)90008-7. [DOI] [PubMed] [Google Scholar]
  4. Hunter S. B., Ballinger W. E., Jr, Rubin J. J. Multiple sclerosis mimicking primary brain tumor. Arch Pathol Lab Med. 1987 May;111(5):464–468. [PubMed] [Google Scholar]
  5. Kesselring J., Miller D. H., Robb S. A., Kendall B. E., Moseley I. F., Kingsley D., du Boulay E. P., McDonald W. I. Acute disseminated encephalomyelitis. MRI findings and the distinction from multiple sclerosis. Brain. 1990 Apr;113(Pt 2):291–302. doi: 10.1093/brain/113.2.291. [DOI] [PubMed] [Google Scholar]
  6. Lidegaard O., Gyldensted C., Juhler M., Zeeberg I. CT findings in acute MS. Acta Neurol Scand. 1983 Aug;68(2):77–83. doi: 10.1111/j.1600-0404.1983.tb04820.x. [DOI] [PubMed] [Google Scholar]
  7. MILLER H. G., EVANS M. J. Prognosis in acute disseminated encephalomyelitis; with a note on neuromyelitis optica. Q J Med. 1953 Jul;22(87):347–379. [PubMed] [Google Scholar]
  8. Ormerod I. E., Miller D. H., McDonald W. I., du Boulay E. P., Rudge P., Kendall B. E., Moseley I. F., Johnson G., Tofts P. S., Halliday A. M. The role of NMR imaging in the assessment of multiple sclerosis and isolated neurological lesions. A quantitative study. Brain. 1987 Dec;110(Pt 6):1579–1616. doi: 10.1093/brain/110.6.1579. [DOI] [PubMed] [Google Scholar]
  9. Sagar H. J., Warlow C. P., Sheldon P. W., Esiri M. M. Multiple sclerosis with clinical and radiological features of cerebral tumour. J Neurol Neurosurg Psychiatry. 1982 Sep;45(9):802–808. doi: 10.1136/jnnp.45.9.802. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Shibasaki H., Kuroda Y., Kuroiwa Y. Clinical studies of multiple sclerosis in Japan: classical multiple sclerosis and Devic's disease. J Neurol Sci. 1974 Oct;23(2):215–222. doi: 10.1016/0022-510x(74)90224-x. [DOI] [PubMed] [Google Scholar]
  11. van der Velden M., Bots G. T., Endtz L. J. Cranial CT in multiple sclerosis showing a mass effect. Surg Neurol. 1979 Oct;12(4):307–310. [PubMed] [Google Scholar]

Articles from Journal of Neurology, Neurosurgery, and Psychiatry are provided here courtesy of BMJ Publishing Group

RESOURCES