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. 2016 Jan 12;7(7):7979–7992. doi: 10.18632/oncotarget.6888

Figure 4. SSA attenuates the inductive effect of TGFβ1 on invasion of MDA-MB-231 cells.

Figure 4

BD Matrigel invasion assay was used to evaluate the motility of MDA-MB-231 cells with different treatments including the vehicle control (0.1% DMSO), SSA (4 μM), TGFβ1 (30 ng/ml), TGFβ1+SSA, and TGFβ1+SB431542 (TGFβ1 receptor inhibitors, 10 μM). Five microscopic fields randomly chosen from each assay were counted individually, and the statistical significance between different treatments and vehicle control was determined by t-test. *P < 0.05.