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Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1992 May;55(5):372–376. doi: 10.1136/jnnp.55.5.372

Assessment of quality of life in patients treated for low-grade glioma: a preliminary report.

M J Taphoorn 1, J J Heimans 1, F J Snoek 1, J Lindeboom 1, B Oosterink 1, J G Wolbers 1, A B Karim 1
PMCID: PMC489078  PMID: 1602310

Abstract

In this pilot study quality of life was assessed in fourteen adult patients who were treated for a low-grade glioma with surgery and radiotherapy at least one year previously. Apart from widely used parameters, such as the neurological and functional status, the patients' cognitive functioning and actual affective status were determined. In addition the patients were interviewed to evaluate various aspects of quality of life. Generally no serious focal neurological deficits were found, although psychological examination showed serious cognitive and affective disturbances in most cases. Self report measures concerning cognitive functioning were not in all cases in accordance with objective test results. When the results of treatment in glioma patients are evaluated assessment of quality of life, including neuropsychological functioning, should be performed, especially as new therapeutic strategies are being developed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Anderson S. W., Damasio H., Tranel D. Neuropsychological impairments associated with lesions caused by tumor or stroke. Arch Neurol. 1990 Apr;47(4):397–405. doi: 10.1001/archneur.1990.00530040039017. [DOI] [PubMed] [Google Scholar]
  2. Benton A. L., Varney N. R., Hamsher K. D. Visuospatial judgment. A clinical test. Arch Neurol. 1978 Jun;35(6):364–367. doi: 10.1001/archneur.1978.00500300038006. [DOI] [PubMed] [Google Scholar]
  3. Cairncross J. G., Laperriere N. J. Low-grade glioma. To treat or not to treat? Arch Neurol. 1989 Nov;46(11):1238–1239. doi: 10.1001/archneur.1989.00520470106035. [DOI] [PubMed] [Google Scholar]
  4. Choucair A. K. Proposals for evaluation of toxic effects associated with treatment of gliomas: a call for action. J Natl Cancer Inst. 1990 Mar 21;82(6):531–532. doi: 10.1093/jnci/82.6.531. [DOI] [PubMed] [Google Scholar]
  5. Danion J. M., Willard-Schroeder D., Zimmermann M. A., Grangé D., Schlienger J. L., Singer L. Explicit memory and repetition priming in depression. Preliminary findings. Arch Gen Psychiatry. 1991 Aug;48(8):707–711. doi: 10.1001/archpsyc.1991.01810320031005. [DOI] [PubMed] [Google Scholar]
  6. DeAngelis L. M., Delattre J. Y., Posner J. B. Radiation-induced dementia in patients cured of brain metastases. Neurology. 1989 Jun;39(6):789–796. doi: 10.1212/wnl.39.6.789. [DOI] [PubMed] [Google Scholar]
  7. Hamsher K. d., Levin H. S., Benton A. L. Facial recognition in patients with focal brain lesions. Arch Neurol. 1979 Dec;36(13):837–839. doi: 10.1001/archneur.1979.00500490051008. [DOI] [PubMed] [Google Scholar]
  8. Hochberg F. H., Slotnick B. Neuropsychologic impairment in astrocytoma survivors. Neurology. 1980 Feb;30(2):172–177. doi: 10.1212/wnl.30.2.172. [DOI] [PubMed] [Google Scholar]
  9. Maire J. P., Coudin B., Guérin J., Caudry M. Neuropsychologic impairment in adults with brain tumors. Am J Clin Oncol. 1987 Apr;10(2):156–162. doi: 10.1097/00000421-198704000-00052. [DOI] [PubMed] [Google Scholar]
  10. North C. A., North R. B., Epstein J. A., Piantadosi S., Wharam M. D. Low-grade cerebral astrocytomas. Survival and quality of life after radiation therapy. Cancer. 1990 Jul 1;66(1):6–14. doi: 10.1002/1097-0142(19900701)66:1<6::aid-cncr2820660103>3.0.co;2-f. [DOI] [PubMed] [Google Scholar]
  11. Shaw E. G., Daumas-Duport C., Scheithauer B. W., Gilbertson D. T., O'Fallon J. R., Earle J. D., Laws E. R., Jr, Okazaki H. Radiation therapy in the management of low-grade supratentorial astrocytomas. J Neurosurg. 1989 Jun;70(6):853–861. doi: 10.3171/jns.1989.70.6.0853. [DOI] [PubMed] [Google Scholar]
  12. Shaw E. G. Low-grade gliomas: to treat or not to treat? A radiation oncologist's viewpoint. Arch Neurol. 1990 Oct;47(10):1138–1140. doi: 10.1001/archneur.1990.00530100108023. [DOI] [PubMed] [Google Scholar]
  13. Sheline G. E., Wara W. M., Smith V. Therapeutic irradiation and brain injury. Int J Radiat Oncol Biol Phys. 1980 Sep;6(9):1215–1228. doi: 10.1016/0360-3016(80)90175-3. [DOI] [PubMed] [Google Scholar]
  14. Smith M. T., Ludwig C. L., Godfrey A. D., Armbrustmacher V. W. Grading of oligodendrogliomas. Cancer. 1983 Dec 1;52(11):2107–2114. doi: 10.1002/1097-0142(19831201)52:11<2107::aid-cncr2820521123>3.0.co;2-x. [DOI] [PubMed] [Google Scholar]
  15. al-Mefty O., Kersh J. E., Routh A., Smith R. R. The long-term side effects of radiation therapy for benign brain tumors in adults. J Neurosurg. 1990 Oct;73(4):502–512. doi: 10.3171/jns.1990.73.4.0502. [DOI] [PubMed] [Google Scholar]
  16. de Haes J. C., van Knippenberg F. C. The quality of life of cancer patients: a review of the literature. Soc Sci Med. 1985;20(8):809–817. doi: 10.1016/0277-9536(85)90335-1. [DOI] [PubMed] [Google Scholar]

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