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. 2016 Feb 14;7(8):8556–8579. doi: 10.18632/oncotarget.7388

Figure 6.

Figure 6

a. The core GEN of young individuals from Figure 2a, as determined by the PNP method, and b. The core GEN of elderly individuals from Figure 3a, as determined by the PNP method. The upper left circle represents the TFs (23), the lower left circle represents the miRNAs (13), and the right circle represents the proteins (155) for the core GEN of young individuals. b. The upper left circle represents the TFs (40), the lower left circle represents the miRNAs (16), and the right circle represents the proteins (119) for the core GEN of elderly individuals. Links within the “proteins” circle represent the significant PPIs, links between the “TFs” circle and the “proteins” circle represent significant regulation of TFs on target genes, and links between the “miRNAs” circle and the “proteins” circle represent significant regulation of miRNAs on target genes in the core GENs of young and elderly individuals.