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. 2016 Feb 14;7(8):8556–8579. doi: 10.18632/oncotarget.7388

Table 1. Pathway analysis of proteins in the GEN of elderly individuals.

Pathway analysis
KEGG pathway Numbers p-value
Pathways in cancer 42 1.7E-4
Neurotrophin signaling pathway 19 2.4E-3
MAPK signaling pathway 32 3.5E-3
NOD-like receptor signaling pathway 12 3.5E-3
Cytosolic DNA-sensing pathway 10 1.4E-2
B cell receptor signaling pathway 12 1.5E-2
ErbB signaling pathway 13 1.8E-2
Toll-like receptor signaling pathway 14 2.4E-2

In the GEN of elderly individuals, the first eight enriched KEGG pathways are pathways in cancer, the Neurotrophin signaling pathway, MAPK signaling pathway, NOD-like receptor signaling pathway, Cytosolic DNA-sensing pathway, B cell receptor signaling pathway, ErbB signaling pathway, and Toll-like receptor signaling pathway.