Table 1. The number of intestinal polyps/mouse in Min mice treated with irsogladine maleate.
Irsogladine maleate (ppm) | No. of polyps/mouse | |||||
---|---|---|---|---|---|---|
No. of mice | Small intestine | Colon | Total | |||
Proximal | Middle | Distal | ||||
0 | 10 | 9.1 ± 3.2 | 14.1 ± 3.8 | 27.4 ± 4.8 | 0.5 ± 0.7 | 51.1 ± 8.1 |
5 | 10 | 3.5 ± 1.9** | 10.2 ± 4.2 | 21.4 ± 5.3* | 0.3 ± 0.5 | 35.4 ± 9.3** |
50 | 10 | 4.2 ± 1.9** | 8.5 ± 2.4** | 20.6 ± 6.7 | 0.5 ± 0.7 | 33.8 ± 8.3* |
Data are presented as the means ± SD.
Significantly different from the untreated control group at
p < 0.05,
p < 0.01.