Skip to main content
. 2016 Apr 1;157(6):2432–2446. doi: 10.1210/en.2015-1942

Figure 6.

Figure 6.

Gap junction inhibition reverses decidualized phenotype and MET changes. Incubation in the presence of a GJIC inhibitor (50 μM 8α-AGA [A]) for 3 or 7 days resulted in a decrease in Cx43 under basal (A3, A7) conditions. E/P/c treatment for 3 or 7 days (H3, H7) increased Cx43, but the latter effect was reversed when AGA also was present from day 4 to day 7 (H7+A3). Similarly, the up-regulation of E-cadherin and ZO1 after 3 and 7 days of E/P/c was blocked when AGA also was present from day 4 to day 7 (H7+A3). CD10 was reduced subtly after 3 or 7 days of E/P/c, with some reversal when AGA also was present from day 4 to day 7 (H7+A3). Expression of β-actin was stable across time and treatments. C, control.