Figure 5.

Effect of light fluence rate and injection interval after PDT on enhanced uptake of nanoparticles: (A) Varying tumor uptake of liposome-ICG with altered light fluence rate in deep-seated tumor models; (B) Tumor: skin ratios of liposome-ICG in mice treated with different light fluence rate; (C) Laser confocal microscopy images of tumor tissues with differing Doxil uptake under NIR light at various light fluence rate; (D) Impact of light fluence rate on intratumoral doxorubicin concentration; (E) Effect of injection interval of nanoparticle after PDT treatment on doxorubicin uptake in tumor tissues.