Skip to main content
. 2016 May 24;6(8):1232–1243. doi: 10.7150/thno.14409

Figure 5.

Figure 5

Combination of erlotinib and trametinib leads to improved efficacy in vivo. A. Mice bearing PC9-v tumors were treated with the indicated drugs for 4 weeks. Tumor growth was measured every week (ten mice per group). *P<0.05, ANOVA followed by Tukey's post-test. B. Mice bearing ER1 or ER2 tumors were treated with the indicated drugs for 4 weeks. Tumor growth was measured every week (ten mice per group). *P<0.05, ANOVA followed by Tukey's post-test. C. Immunohistochemical staining of Ki-67 and cleaved caspase-3 in tumor xenograft sections.