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FAIRE profile of latent ICP0-expressing and ICP0 mutant genomes. Chromatin from latently infected trigeminal ganglia was evaluated by FAIRE to compare the proportion of nucleosome-free viral DNA relative to the total input viral DNA amount in ICP0-expressing (PromR or n212R) and ICP0 mutant (dProm or n212) viruses. FAIRE results are presented for ICP8 (A) and LAP (B) regions.
