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. 1993 Jun;56(6):713–716. doi: 10.1136/jnnp.56.6.713

Paraneoplastic cerebellar degeneration and limbic encephalitis in a patient with adenocarcinoma of the colon.

T Tsukamoto 1, R Mochizuki 1, H Mochizuki 1, M Noguchi 1, H Kayama 1, M Hiwatashi 1, T Yamamoto 1
PMCID: PMC489629  PMID: 8509793

Abstract

The rare association of two neurological paraneoplastic syndromes, paraneoplastic cerebellar degeneration and limbic encephalitis occurred in a 55 year old woman with a microscopic adenocarcinoma in a colonic polyp. Complete removal of the tumour by polypectomy brought about a favourable recovery from limbic encephalitis but the cerebellar ataxia remained. High titres of antineuronal nuclear antibody resembling anti-Hu were demonstrated in serum by immunohistochemistry using rat brain as a substrate. The antibody identified a protein band of 41 kDa on a Western immunoblot.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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