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Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1993 Nov;56(11):1213–1216. doi: 10.1136/jnnp.56.11.1213

Intermittent high-dose vitamin C therapy in patients with HTLV-I associated myelopathy.

A Kataoka 1, H Imai 1, S Inayoshi 1, T Tsuda 1
PMCID: PMC489823  PMID: 8229033

Abstract

The efficacy of intermittent high-dose vitamin C therapy was evaluated in seven patients with HTLV-I-associated myelopathy (HAM). All HAM patients responded well to this therapy without serious side effects. Grade of disability score improved at 9.7 (SD 5.8) months after the therapy from 7.1 (3.3) to 3.6 (2.0) (p < 0.01). Serum immunosuppressive acidic protein was elevated before and decreased after the therapy from 747 (316) to 398 (86) micrograms/ml (p < 0.05), suggesting favourable immunomodulatory action of vitamin C therapy in HAM patients.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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