Table 1. Percentage of RBCs with PS-exposure as measured with annexin V and lactadherin on transfused, untransfused and in vitro biotin labelled RBCs.

		Before Transfusion		After Transfusion
PS-exposure		Unlabeled and untransfused RBCs sampled from circulation	BioRBCs only	Unlabeled RBCs from circulation	BioRBCs isolated from circulation
Lactadherin (%)	Control	0.20 (0.19-0.29)	N/A	0.20 (0.14-0.26)	N/A
	2D RBCs	0.20 (0.15-0.39)	0.30 (0.11-0.57)	0.17 (0.12-0.42)	0.70 (0.00-2.43)
	35D RBCs	0.20 (0.01-0.76)	0.20 (0.05-0.37)	0.59 (0.00-0.98)	0.85 (0.00-5.02)
Annexin V (%)	Control	0.30 (0.18-0.58)	N/A	0.30 (0.15-0.49)	N/A
	2D RBCs	1.30 (0.90-1.44)	0.65 (0.63-0.76)	1.30 (0.85-1.47)	0.70 (0.51-0.91)
	35D RBCs	1.20 (0.37-0.97)	0.80 (0.76-0.91)	1.10 (0.87-1.29)	0.50 (0.32-0.90)

^*The column “Before Transfusion” describes the background lactadherin and CD47 expression on naïve RBCs drawn from the circulation and BioRBCs directly after labeling. The column “After Transfusion” describes the sample which has been drawn after transfusion from which both BioRBCs and unlabeled RBCs have been isolated. Values are expressed as medians and confidence intervals between brackets.