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Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1979 Jun;42(6):542–547. doi: 10.1136/jnnp.42.6.542

Crural hypertrophy associated with centronuclear myopathy

P Bill 1,2,3,4, G Cole 1,2,3,4, N S F Proctor 1,2,3,4, D Saffer 1,2,3,4, A Botes 1,2,3,4
PMCID: PMC490259  PMID: 157387

Abstract

A case of centronuclear myopathy of adult onset with striking hypertrophy of lower limb muscles in a black South African man is described with details of the light microscopic, histochemical, and ultrastructural features. The association of hypertrophied muscles with centronuclear myopathy has not to our knowledge been reported previously and it is felt that this may be a variant of the condition.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bill P. L., Cole G., Proctor N. S. Centronuclear myopathy. J Neurol Neurosurg Psychiatry. 1979 Jun;42(6):548–556. doi: 10.1136/jnnp.42.6.548. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Harriman D. G., Haleem M. A. Centronuclear myopathy in old age. J Pathol. 1972 Nov;108(3):237–247. doi: 10.1002/path.1711080309. [DOI] [PubMed] [Google Scholar]
  3. Headington J. T., McNamara J. O., Brownell A. K. Centronuclear myopathy: histochemistry and electron microscopy. Report of two cases. Arch Pathol. 1975 Jan;99(1):16–24. [PubMed] [Google Scholar]
  4. McLeod J. G., Baker W. de C., Lethlean A. K., Shorey C. D. Centronuclear myopathy with autosomal dominant inheritance. J Neurol Sci. 1972 Apr;15(4):375–387. doi: 10.1016/0022-510x(72)90166-9. [DOI] [PubMed] [Google Scholar]
  5. Pearn J., Hudgson P. Anterior-horn cell degeneration and gross calf hypertrophy with adolescent onset. A new spinal muscular atrophy syndrome. Lancet. 1978 May 20;1(8073):1059–1061. doi: 10.1016/s0140-6736(78)90910-8. [DOI] [PubMed] [Google Scholar]
  6. van Wijngaarden G. K., Fleury P., Bethlem J., Meijer A. E. Familial "myotubular" myopathy. Neurology. 1969 Sep;19(9):901–908. doi: 10.1212/wnl.19.9.901. [DOI] [PubMed] [Google Scholar]

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