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. 1979 Jul;42(7):656–661. doi: 10.1136/jnnp.42.7.656

Cutaneous sensory function in diabetes mellitus.

J P Conomy, K L Barnes, J M Conomy
PMCID: PMC490281  PMID: 479906

Abstract

That disorders of cutaneous sensation are common in diabetes mellitus can be substantiated by quantitative cutaneous sensory testing. Cutaneous sensory disturbances are not clearly related to clinical factors such as the type, treatment, or duration of diabetes, or ocular complications. Diabetics can be distinguished from nondiabetics on quantitative examination of skin sensation. Juvenile diabetics appear to have fewer cutaneous abnormalities than adults who develop the disease, but the juvenile diabetic is not spared. Disorders of cutaneous sensation may represent a fundamental abnormality of the nervous system in diabetes mellitus. While altered peripheral sensory mechanisms are likely, abnormality of central sensory processing is not excluded by the results of this study.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BUSCHMANN G., FRITZE E., MARSCH A. Verlaufsbeobachtungen an 1500 Zuckerkranken. Dtsch Med Wochenschr. 1958 Jul 25;83(30):1284–1289. doi: 10.1055/s-0028-1113771. [DOI] [PubMed] [Google Scholar]
  2. COLBY A. O. NEUROLOGIC DISORDERS OF DIABETES MELLITUS. II. Diabetes. 1965 Aug;14:516–CONTD. doi: 10.2337/diab.14.8.516. [DOI] [PubMed] [Google Scholar]
  3. COLLENS W. S., ZILINSKY J. D., BOAS L. C., GREENWALD J. J. Impaired vibratory sense in diabetes mellitus with proteinuria. J Clin Invest. 1950 Jun;29(6):723–725. doi: 10.1172/JCI102309. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Chochinov R. H., Ullyot G. L., Moorhouse J. A. Sensory perception thresholds in patients with juvenile diabetes and their close relatives. N Engl J Med. 1972 Jun 8;286(23):1233–1237. doi: 10.1056/NEJM197206082862303. [DOI] [PubMed] [Google Scholar]
  5. Conomy J. P., Barnes K. L., Cruse R. P. Quantitative cutaneous sensory testing in children and adolescents. Cleve Clin Q. 1978 Summer;45(2):197–206. doi: 10.3949/ccjm.45.2.197. [DOI] [PubMed] [Google Scholar]
  6. Conomy J. P., Barnes K. L. Quantitative assessment of cutaneous sensory function in subjects with neurologic disease. J Neurol Sci. 1976 Dec;30(2-3):221–235. doi: 10.1016/0022-510x(76)90129-5. [DOI] [PubMed] [Google Scholar]
  7. Conomy J. P., Barnes K. A technique for the quantitative assessment of cutaneous sensory function in subjects with neurologic disease. Trans Am Neurol Assoc. 1974;99:83–87. [PubMed] [Google Scholar]
  8. Cruse R. P., Conomy J. P., Wilbourn A. J., Hanson M. R. Hereditary hypertrophic neuropathy combining features of tic douloureux, Charcot-Marie-Tooth disease, and deafness. Cleve Clin Q. 1977 Fall;44(3):107–111. doi: 10.3949/ccjm.44.3.107. [DOI] [PubMed] [Google Scholar]
  9. Deckert T., Poulsen J. E., Larsen M. Prognosis of diabetics with diabetes onset before the age of thirty-one. II. Factors influencing the prognosis. Diabetologia. 1978 Jun;14(6):371–377. doi: 10.1007/BF01228131. [DOI] [PubMed] [Google Scholar]
  10. Heinrichs R. W., Moorhouse J. A. Touch-perception thresholds in blind diabetic subjects in relation to the reading of Braille type. N Engl J Med. 1969 Jan 9;280(2):72–75. doi: 10.1056/NEJM196901092800204. [DOI] [PubMed] [Google Scholar]
  11. MARTIN M. M. Diabetic neuropathy; a clinical study of 150 cases. Brain. 1953;76(4):594–624. doi: 10.1093/brain/76.4.594. [DOI] [PubMed] [Google Scholar]
  12. MICHON P., LARCAN A., HURIET C., VICARI F., VERT P. [Diabetic neuropathies. Statistics concerning 498 cases of diabetes]. Bull Mem Soc Med Hop Paris. 1961 Apr 14;77:433–441. [PubMed] [Google Scholar]
  13. MULDER D. W., LAMBERT E. H., BASTRON J. A., SPRAGUE R. G. The neuropathies associated with diabetes mellitus. A clinical and electromyographic study of 103 unselected diabetic patients. Neurology. 1961 Apr;11(4):275–284. doi: 10.1212/wnl.11.4.275. [DOI] [PubMed] [Google Scholar]
  14. Milner R. D. Diabetes mellitus in adolescence. J R Coll Physicians Lond. 1978 Apr;12(3):240–245. [PMC free article] [PubMed] [Google Scholar]
  15. Parmley W. W., Glick G., Sonnenblick E. H. Cardiovascular effects of glucagon in man. N Engl J Med. 1968 Jul 4;279(1):12–17. doi: 10.1056/NEJM196807042790103. [DOI] [PubMed] [Google Scholar]
  16. SULLIVAN J. F. The neuropathies of diabetes. Neurology. 1958 Apr;8(4):243–249. doi: 10.1212/wnl.8.4.243. [DOI] [PubMed] [Google Scholar]
  17. Winegrad A. I., Greene D. A. Diabetic polyneuropathy: the importance of insulin deficiency, hyperglycemia and alterations in myoinositol metabolism in its pathogenesis. N Engl J Med. 1976 Dec 16;295(25):1416–1421. doi: 10.1056/NEJM197612162952507. [DOI] [PubMed] [Google Scholar]

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