QOS-37: VALIDATION OF A PARENT- AND SELF-REPORT COGNITIVE FUNCTION QUESTIONNAIRE AS A ROUTINE ASSESSMENT OF COGNITIVE DYSFUNCTION

Cognitive dysfunction is a common concern for Pediatric brain tumor survivors (PBTS). In the Netherlands, PBTS undergo standardized neuropsychological screening based on international protocols (COG, ALTE 07C1 Cure Search). However, this is extremely time and resource consuming. Initial screening with a questionnaire might detect children who actually need neuropsychological testing and allow for personalized test-batteries. We assess the usefulness of the perceived cognitive function item-bank (pedsPCF) to screen for neuropsychological dysfunction. We administered the Dutch child and parent pedsPCF (43 items, 5-point Likert-scale, memory retrieval-, attention/concentration-, and working memory factor) alongside the neuropsychological screening protocol in PBTS of 7-18 years old in the Emma-, and Sophia children's hospitals, and VU Medical Center. We analyzed whether the child and parent pedsPCF related to neuropsychological measures of processing speed, sustained-, and divided attention, verbal- and visual-spatial memory, and planning. Preliminary analyses (N = 15) showed correlations (r) ranging from -.76 to .51 (PedsPCF-child), and -.47 to .35 (PedsPCF-parent). Significant correlations were found between the PedsPCF-child total scale and sustained attention, verbal memory, and planning; the memory retrieval factor and verbal, but not visual-spatial memory; and the attention/concentration factor and sustained-, but not divided attention. The PedsPCF-parent, the working memory scale, and divided attention were not significantly related to other measures. Hence, significant relations were found between the pedsPCF and some, but not all neuropsychological measures. The PedsPCF-child might better screen neuropsychological dysfunction than the PedsPCF-parent, which we currently study in a larger number of participants.