Skip to main content
Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1980 Jan;43(1):76–81. doi: 10.1136/jnnp.43.1.76

Haemorrhagic complications of multiple sclerosis.

J Jankovic, H Derman, D Armstrong
PMCID: PMC490467  PMID: 7354362

Abstract

Neurological exacerbations in multiple sclerosis patients are usually attributed to relapses of the disease. This report emphasises that other conditions, such as spontaneous CNS haemorrhage, may be responsible for the clinical deterioration. We describe two patients appropriately diagnosed as having multiple sclerosis who developed spontaneous CNS haemorrhage.

Full text

PDF
76

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Abroms I. F., Yessayan L., Shillito J., Barlow C. F. Spontaneous intracerebral haemorrhage in patients suspected of multiple sclerosis. J Neurol Neurosurg Psychiatry. 1971 Apr;34(2):157–162. doi: 10.1136/jnnp.34.2.157. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Aita J. F., Bennett D. R., Anderson R. E., Ziter F. Cranial CT appearance of acute multiple sclerosis. Neurology. 1978 Mar;28(3):251–255. doi: 10.1212/wnl.28.3.251. [DOI] [PubMed] [Google Scholar]
  3. Cendrowski W., Stepień M. Clinical variant of lupus erythematosus resembling multiple sclerosis. Eur Neurol. 1974;11(6):373–376. doi: 10.1159/000114336. [DOI] [PubMed] [Google Scholar]
  4. FELDMAN S., IZAK G., NELKEN D. Blood coagulation studies and serotonin determinations in serum and cerebrospinal fluid in multiple sclerosis. Acta Psychiatr Neurol Scand. 1957;32(1):37–49. doi: 10.1111/j.1600-0447.1957.tb07543.x. [DOI] [PubMed] [Google Scholar]
  5. FOG T., KRISTENSEN I., HELWEG-LARSEN H. F. Blood platelets in disseminated sclerosis; quantitative variations in peripheral blood. AMA Arch Neurol Psychiatry. 1955 Mar;73(3):267–285. doi: 10.1001/archneurpsyc.1955.02330090013002. [DOI] [PubMed] [Google Scholar]
  6. Fulford K. W., Catterall R. D., Delhanty J. J., Doniach D., Kremer M. A collagen disorder of the nervous system presenting as multiple sclerosis. Brain. 1972;95(2):373–386. doi: 10.1093/brain/95.2.373. [DOI] [PubMed] [Google Scholar]
  7. Johnson R. T., Richardson E. P. The neurological manifestations of systemic lupus erythematosus. Medicine (Baltimore) 1968 Jul;47(4):337–369. doi: 10.1097/00005792-196807000-00002. [DOI] [PubMed] [Google Scholar]
  8. Lebow S., Anderson D. C., Mastri A., Larson D. Acute multiple sclerosis with contrast-enhancing plaques. Arch Neurol. 1978 Jul;35(7):435–439. doi: 10.1001/archneur.1978.00500310037007. [DOI] [PubMed] [Google Scholar]
  9. Lehman R. A., Fieger H. G., Jr Arachnoid cyst producing recurrent neurological disturbances. Surg Neurol. 1978 Aug;10(2):134–136. [PubMed] [Google Scholar]
  10. MACCHI G. The pathology of the blood vessels in multiple sclerosis. J Neuropathol Exp Neurol. 1954 Apr;13(2):378–384. doi: 10.1097/00005072-195404000-00008. [DOI] [PubMed] [Google Scholar]
  11. Menon I. S., Dewar H. A., Newell D. J. Fibrinolytic activity of venous blood of patients with multiple sclerosis. Neurology. 1969 Jan;19(1):101–104. doi: 10.1212/wnl.19.1.101. [DOI] [PubMed] [Google Scholar]
  12. Millac P. Platelet stickiness in multiple sclerosis. Dtsch Z Nervenheilkd. 1967;191(1):74–79. doi: 10.1007/BF00243772. [DOI] [PubMed] [Google Scholar]
  13. Millar J. H., Merrett J. D., Dalby A. M. Platelet stickiness in multiple sclerosis. J Neurol Neurosurg Psychiatry. 1966 Jun;29(3):187–189. doi: 10.1136/jnnp.29.3.187. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. PERSSON I. Variations in the plasma fibrinogen during the course of multiple sclerosis. AMA Arch Neurol Psychiatry. 1955 Jul;74(1):17–30. doi: 10.1001/archneurpsyc.1955.02330130019004. [DOI] [PubMed] [Google Scholar]
  15. Reagan T. J., Freiman I. S. Multiple cerebral gliomas in multiple sclerosis. J Neurol Neurosurg Psychiatry. 1973 Aug;36(4):523–528. doi: 10.1136/jnnp.36.4.523. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. SHULMAN M. H., ALEXANDER L., EHRENTHEIL O. F., GROSS R. Capillary resistance studies in multiple sclerosis. J Neuropathol Exp Neurol. 1950 Oct;9(4):420–429. doi: 10.1097/00005072-195010000-00007. [DOI] [PubMed] [Google Scholar]
  17. SWANK R. L. Subcutaneous hemorrhages in multiple sclerosis. Neurology. 1958 Jun;8(6):497–498. doi: 10.1212/wnl.8.6.497. [DOI] [PubMed] [Google Scholar]
  18. Sears E. S., Tindall R. S., Zarnow H. Active multiple sclerosis. Enhanced computerized tomographic imaging of lesions and the effect of corticosteroids. Arch Neurol. 1978 Jul;35(7):426–434. doi: 10.1001/archneur.1978.00500310028006. [DOI] [PubMed] [Google Scholar]
  19. Sibley W. A., Kiernat J., Laguna J. F. The modification of experimental allergic encephalomyelitis with epsilon aminocaproic acid. Neurology. 1978 Sep;28(9 Pt 2):102–105. doi: 10.1212/wnl.28.9_part_2.102. [DOI] [PubMed] [Google Scholar]
  20. Waisburg H., Meloff K. L., Buncic R. Polyarteritis nodosa complicated by a multiple sclerosis like syndrome. Can J Neurol Sci. 1974 Nov;1(4):250–252. doi: 10.1017/s0317167100019855. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Neurology, Neurosurgery, and Psychiatry are provided here courtesy of BMJ Publishing Group

RESOURCES