Table 1. Association of OGTT glucose or IL-6-producing T cells with clinical parameters (univariate linear regression analyses).

Parameters		Unstandardized coefficient (95% CI)	Linear regression coefficient (r)	P
OGTT glucose	IL-6-producing T cells§	4.799 (3.37 to 6.23)	0.711	<0.001***
	TG	−0.007 (−0.29 to 0.28)	0.010	0.957
	BMI	2.550 (−3.87 to 8.96)	0.124	0.427
	Waist	1.863 (−1.91 to 3.27)	0.083	0.600
	Fasting insulin	1.952 (−7.09 to 11.00)	0.070	0.665
	ISSI-2	−0.173 (−0.22 to −0.13)	−0.762	<0.001***
	HOMA-IR	14.761 (2.45 to 27.06)	−0.339	<0.001***
	HOMA-IR#	21.517 (10.92 to 32.11)	0.539	<0.001***
IL-6-producing T cells§	OGTT glucose	4.799 (3.37 to 6.23)	0.711	<0.001***
	TG	−0.024 (−0.06 to 0.02)	0.217	0.223
	BMI	0.188 (−0.70 to 1.07)	0.067	0.670
	Waist	0.020 (−0.33 to 0.37)	0.018	0.910
	Fasting insulin	0.013 (−0.48 to 0.51)	0.008	0.959
	ISSI-2	−0.011 (−0.01 to −0.002)	−0.357	0.023*
	HOMA-IR	0.829 (−1.09 to 2.75)	0.128	0.389
	HOMA-IR#	2.285 (1.12 to 3.45)	0.526	<0.001***

The clinical results — including TG, BMI, waist circumference, ISSI-2, fasting insulin, HOMA-IR, and IL-6-producing T cells — from 48 individuals (18 healthy controls, 13 IGT, and 17 T2D patients) were analyzed using univariate linear regression. §, removing one outlier that showed high residual value (modulus = 220.762 > 100; standardized residual = 4.173 > 3). #, excluding four T2D patients' data with the lowest 25% HOMA-β values (< 35). CI denotes confidence intervals. BMI, body mass index. TG, triglyceride levels. Waist, waist circumference. ISSI-2, insulin secretion-sensitivity index-2. HOMA-IR, homeostatic model assessment of insulin resistance. *, P value < 0.05; **, P value < 0.01; ***, P value < 0.001.