Skip to main content
Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1980 Sep;43(9):846–848. doi: 10.1136/jnnp.43.9.846

Dementia associated with Parkinson's disease: a genetic study.

L L Heston
PMCID: PMC490678  PMID: 7420108

Abstract

Relatives of 12 probands who had severe dementia associated with Parkinson's disease were studied. A high risk for Parkinson's disease was found among relatives but only one instance of dementia. The high risk to relatives and the dementia of the probands appeared to be related to the overall severity of the Parkinsonian illness.

Full text

PDF
846

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Heston L. L., Mastri A. R. The genetics of Alzheimer's disease: associations with hematologic malignancy and Down's syndrome. Arch Gen Psychiatry. 1977 Aug;34(8):976–981. doi: 10.1001/archpsyc.1977.01770200114017. [DOI] [PubMed] [Google Scholar]
  2. Hoehn M. M., Yahr M. D. Parkinsonism: onset, progression and mortality. Neurology. 1967 May;17(5):427–442. doi: 10.1212/wnl.17.5.427. [DOI] [PubMed] [Google Scholar]
  3. Kondo K., Kurland L. T., Schull W. J. Parkinson's disease. Genetic analysis and evidence of a multifactorial etiology. Mayo Clin Proc. 1973 Jul;48(7):465–475. [PubMed] [Google Scholar]
  4. Martin W. E., Young W. I., Anderson V. E. Parkinson's disease. A genetic study. Brain. 1973 Sep;96(3):495–506. doi: 10.1093/brain/96.3.495. [DOI] [PubMed] [Google Scholar]
  5. Pollock M., Hornabrook R. W. The prevalence, natural history and dementia of Parkinson's disease. Brain. 1966 Sep;89(3):429–448. doi: 10.1093/brain/89.3.429. [DOI] [PubMed] [Google Scholar]
  6. Stern S. L., Hurtig H. I., Mendels J., Balaban D. Psychiatric illness in relatives of patients with Parkinson's disease: a preliminary report. Am J Psychiatry. 1977 Apr;134(4):443–444. doi: 10.1176/ajp.134.4.443. [DOI] [PubMed] [Google Scholar]
  7. Young W. I., Martin W. E., Anderson V. E. The distribution of ancestral secondary cases in Parkinson's disease. Clin Genet. 1977 Mar;11(3):189–192. doi: 10.1111/j.1399-0004.1977.tb01298.x. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Neurology, Neurosurgery, and Psychiatry are provided here courtesy of BMJ Publishing Group

RESOURCES