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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1992 May 15;89(10):4300–4303. doi: 10.1073/pnas.89.10.4300

Selection-induced mutations occur in yeast.

B G Hall 1
PMCID: PMC49069  PMID: 1584764

Abstract

Selection-induced mutations are nonrandom mutations that occur as specific and direct responses to environmental challenges and primarily in nondividing cells under conditions of intense prolonged selection. Selection-induced mutations have been shown to occur at six loci in Escherichia coli, but their existence has not previously been demonstrated in any eukaryotic organism. Here it is shown that selection-induced mutations occur at the HIS4 locus in the eukaryotic microorganism Saccharomyces cerevisiae.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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