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. 1979 Mar;42(3):203–207. doi: 10.1136/jnnp.42.3.203

Cellular hypersensitivity to brain antigen in children of a family with hereditary ataxia

R S Walls 1, D V Philcox 1, Catherine L Cullis 1
PMCID: PMC490721  PMID: 374687

Abstract

Sensitisation to brain antigen was demonstrated in eight of 24 clinically normal first generation children in a family with hereditary ataxia. This ratio is consistent with that expected in a dominantly inherited condition. It suggests that immunological reactivity may precede the clinical expression of disease, with important implications for presymptomatic diagnosis and for pathogenesis of degenerative disease.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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