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Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1980 Nov;43(11):1012–1015. doi: 10.1136/jnnp.43.11.1012

Abnormal regulation of prolactin release in idiopathic Parkinson's disease.

N F Lawton, J MacDermot
PMCID: PMC490753  PMID: 6777462

Abstract

Levodopa with carbidopa suppressed prolactin release induced by thyrotrophin releasing hormone less effectively in patients with idiopathic Parkinson's disease than in normal subjects. This finding supports the view that the biochemical defect in idiopathic Parkinson's disease extends to the hypothalamus and is not confined to the basal ganglia. Aetiological considerations in Parkinson's disease should encompass a widespread disorder of neurotransmission whose extent merits further investigation.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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