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. 1981 May;44(5):451–455. doi: 10.1136/jnnp.44.5.451

Aspergillus granuloma of the trigeminal ganglion

C M Wiles 1,2,3, R S Kocen 1,2,3, L Symon 1,2,3, F Scaravilli 1,2,3
PMCID: PMC490994  PMID: 6973615

Abstract

A patient is described with aspergillus flavus granuloma of the trigeminal ganglion. The patient was effectively treated by surgical excision of most of the infected tissue followed by intensive chemotherapy with amphotericin B and flucytosine.

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Selected References

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  1. Aisner J., Murillo J., Schimpff S. C., Steere A. C. Invasive aspergillosis in acute leukemia: correlation with nose cultures and antibiotic use. Ann Intern Med. 1979 Jan;90(1):4–9. doi: 10.7326/0003-4819-90-1-4. [DOI] [PubMed] [Google Scholar]
  2. Atkinson A. J., Jr, Bennett J. E. Amphotericin B pharmacokinetics in humans. Antimicrob Agents Chemother. 1978 Feb;13(2):271–276. doi: 10.1128/aac.13.2.271. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Aung U. K., Lin U. K., Nyunt U. S. Letpomeningeal aspergillosis causing internal carotid artery stenosis. Br J Radiol. 1979 Apr;52(616):328–329. doi: 10.1259/0007-1285-52-616-328. [DOI] [PubMed] [Google Scholar]
  4. Bennett J. E. Chemotherapy of systemic mycoses (second of two parts). N Engl J Med. 1974 Feb 7;290(6):320–323. doi: 10.1056/NEJM197402072900607. [DOI] [PubMed] [Google Scholar]
  5. Burton J. R., Zachery J. B., Bessin R., Rathbun H. K., Greenough W. B., 3rd, Sterioff S., Wright J. R., Slavin R. E., Williams G. M. Aspergillosis in four renal transplant recipients. Diagnosis and effective treatment with amphotericin B. Ann Intern Med. 1972 Sep;77(3):383–388. doi: 10.7326/0003-4819-77-3-383. [DOI] [PubMed] [Google Scholar]
  6. Davidson P., Robertson D. M. A true mycotic (Aspergillus) aneurysm leading to fatal subarachnoid hemorrhage in a patient with hereditary hemorrhagic telangiectasia. Case report. J Neurosurg. 1971 Jul;35(1):71–76. doi: 10.3171/jns.1971.35.1.0071. [DOI] [PubMed] [Google Scholar]
  7. Dayal Y., Weindling H. K., Price D. L. Cerebral infarction due to fungal embolus. A complication of Aspergillus infection on an aortic valve prosthesis. Neurology. 1974 Jan;24(1):76–79. doi: 10.1212/wnl.24.1.76. [DOI] [PubMed] [Google Scholar]
  8. Feely M., Steinberg M. Aspergillus infection complicating trassphenoidal yttrium-90 pituitary implant. Report of two cases. J Neurosurg. 1977 Apr;46(4):530–532. doi: 10.3171/jns.1977.46.4.0530. [DOI] [PubMed] [Google Scholar]
  9. Grigoriu D., Bambule J., Delacretaz J. Aspergillus sinusitis. Postgrad Med J. 1979 Sep;55(647):619–621. doi: 10.1136/pgmj.55.647.619. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Hedges T. R., Leung L. S. Parasellar and orbital apex syndrome caused by aspergillosis. Neurology. 1976 Feb;26(2):117–120. doi: 10.1212/wnl.26.2.117. [DOI] [PubMed] [Google Scholar]
  11. Horten B. C., Abbott G. F., Porro R. S. Fungal aneurysms of intracranial vessels. Arch Neurol. 1976 Aug;33(8):577–579. doi: 10.1001/archneur.1976.00500080055008. [DOI] [PubMed] [Google Scholar]
  12. IYER S., DODGE P. R., ADAMS R. D. Two cases of Aspergillus infection of the central nervous system. J Neurol Neurosurg Psychiatry. 1952 Aug;15(3):152–163. doi: 10.1136/jnnp.15.3.152. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Ingwer I., McLeish K. R., Tight R. R., White A. C. Aspergillus fumigatus epidural abscess in a renal transplant recipient. Arch Intern Med. 1978 Jan;138(1):153–154. [PubMed] [Google Scholar]
  14. Kammer R. B., Utz J. P. Aspergillus species endocarditis. The new face of a not so rare disease. Am J Med. 1974 Apr;56(4):506–521. doi: 10.1016/0002-9343(74)90483-5. [DOI] [PubMed] [Google Scholar]
  15. Kaufman D. M., Thal L. J., Farmer P. M. Central nervous system aspergillosis in two young adults. Neurology. 1976 May;26(5):484–488. doi: 10.1212/wnl.26.5.484. [DOI] [PubMed] [Google Scholar]
  16. Lauer B. A., Reller L. B., Schröter G. P. Susceptibility of Aspergillus to 5-fluorocytosine and amphotericin B alone and in combination. J Antimicrob Chemother. 1978 Jul;4(4):375–380. doi: 10.1093/jac/4.4.375. [DOI] [PubMed] [Google Scholar]
  17. Linares G., McGarry P. A., Baker R. D. Solid solitary aspergillotic granuloma of the brain. Report of a case due to Aspergillus candidus and review of the literature. Neurology. 1971 Feb;21(2):177–184. doi: 10.1212/wnl.21.2.177. [DOI] [PubMed] [Google Scholar]
  18. MacCormick W. F., Schochet S. S., Jr, Weaver P. R., MacCrary J. A., 3rd Disseminated aspergillosis. Aspergillus endophthalmitis, optic nerve infarction, and carotid artery thrombosis. Arch Pathol. 1975 Jul;99(7):353–359. [PubMed] [Google Scholar]
  19. Mackenzie D. W. Imported fungal infections. Postgrad Med J. 1979 Sep;55(647):595–597. doi: 10.1136/pgmj.55.647.595. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. McKEE E. E. Mycotic infection of brain with arteritis and subarachnoid hemorrhage; report of case. Am J Clin Pathol. 1950 Apr;20(4):381–384. doi: 10.1093/ajcp/20.4.381. [DOI] [PubMed] [Google Scholar]
  21. Med M. Prenatal development of lumbar intervertebral articulation. Folia Morphol (Praha) 1982;30(3):285–290. [PubMed] [Google Scholar]
  22. Medoff G., Kobayashi G. S. Strategies in the treatment of systemic fungal infections. N Engl J Med. 1980 Jan 17;302(3):145–155. doi: 10.1056/NEJM198001173020304. [DOI] [PubMed] [Google Scholar]
  23. Meyer R. D., Young L. S., Armstrong D., Yu B. Aspergillosis complicating neoplastic disease. Am J Med. 1973 Jan;54(1):6–15. doi: 10.1016/0002-9343(73)90077-6. [DOI] [PubMed] [Google Scholar]
  24. Milosev B., el-Mahgoub S., Aal O. A., el-Hassan A. M. Primary aspergilloma of paranasal sinuses in the Sudan. A review of seventeen cases. Br J Surg. 1969 Feb;56(2):132–137. doi: 10.1002/bjs.1800560213. [DOI] [PubMed] [Google Scholar]
  25. Miloshev B., Davidson C. M., Gentles J. C., Sandison A. T. Aspergilloma of paranasal sinuses and orbit in Northern Sudanese. Lancet. 1966 Apr 2;1(7440):746–747. doi: 10.1016/s0140-6736(66)90898-1. [DOI] [PubMed] [Google Scholar]
  26. Mohandas S., Ahuja G. K., Sood V. P., Virmani V. Aspergillosis of the central nervous system. J Neurol Sci. 1978 Sep;38(2):229–233. doi: 10.1016/0022-510x(78)90069-2. [DOI] [PubMed] [Google Scholar]
  27. Mukoyama M., Gimple K., Poser C. M. Aspergillosis of the central nervous system. Report of a brain abscess due to A. fumigatus and review of the literature. Neurology. 1969 Oct;19(10):967–974. doi: 10.1212/wnl.19.10.967. [DOI] [PubMed] [Google Scholar]
  28. Olivero J. J., Lozano-Mendez J., Ghafary E. M., Eknoyan G., Suki W. N. Mitigation of amphotericin B nephrotoxicity by mannitol. Br Med J. 1975 Mar 8;1(5957):550–551. doi: 10.1136/bmj.1.5957.550. [DOI] [PMC free article] [PubMed] [Google Scholar]
  29. Polak A. Pharmacokinetics of amphotericin B and flucytosine. Postgrad Med J. 1979 Sep;55(647):667–670. doi: 10.1136/pgmj.55.647.667. [DOI] [PMC free article] [PubMed] [Google Scholar]
  30. Rifkind D., Marchioro T. L., Schneck S. A., Hill R. B., Jr Systemic fungal infections complicating renal transplantation and immunosuppressive therapy. Clinical, microbiologic, neurologic and pathologic features. Am J Med. 1967 Jul;43(1):28–38. doi: 10.1016/0002-9343(67)90146-5. [DOI] [PubMed] [Google Scholar]
  31. Rosch J. M., Pazin G. J., Fireman P. Reduction of amphotericin B nephrotoxicity with mannitol. JAMA. 1976 May 3;235(18):1995–1996. [PubMed] [Google Scholar]
  32. Turner-Warwick M. Aspergillus fumigatus and lung disease. Postgrad Med J. 1979 Sep;55(647):642–644. doi: 10.1136/pgmj.55.647.642. [DOI] [PMC free article] [PubMed] [Google Scholar]
  33. Visudhiphan P., Bunyaratavej S., Khantanaphar S. Cerebral aspergillosis. Report of three cases. J Neurosurg. 1973 Apr;38(4):472–476. doi: 10.3171/jns.1973.38.4.0472. [DOI] [PubMed] [Google Scholar]
  34. WYBEL R. E. Mycosis of cervical spinal cord following intrathecal penicillin therapy; report of a case simulating cord tumor. AMA Arch Pathol. 1952 Feb;53(2):167–173. [PubMed] [Google Scholar]
  35. Young R. C., Bennett J. E., Vogel C. L., Carbone P. P., DeVita V. T. Aspergillosis. The spectrum of the disease in 98 patients. Medicine (Baltimore) 1970 Mar;49(2):147–173. doi: 10.1097/00005792-197003000-00002. [DOI] [PubMed] [Google Scholar]

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